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Cyclin K inhibits HIV-1 gene expression and replication by interfering with cyclin-dependent kinase 9 (CDK9)-cyclin T1 interaction in Nef-dependent mannerDirect binding of human immunodeficiency virus type 1 Nef to the major histocompatibility complex class I (MHC-I) cytoplasmic tail disrupts MHC-I traffickingc-Src protein kinase inhibitors block assembly and maturation of dengue virusAnti-CD45RO suppresses human immunodeficiency virus type 1 replication in microglia: role of Hck tyrosine kinase and implications for AIDS dementia.Mapping the binding site of full length HIV-1 Nef on human Lck SH3 by NMR spectroscopy.Simian immunodeficiency virus containing mutations in N-terminal tyrosine residues and in the PxxP motif in Nef replicates efficiently in rhesus macaques.The HIV Nef protein alters Ca(2+) signaling in myelomonocytic cells through SH3-mediated protein-protein interactions.Role of the SH3-ligand domain of simian immunodeficiency virus Nef in interaction with Nef-associated kinase and simian AIDS in rhesus macaquesDesign and use of an inducibly activated human immunodeficiency virus type 1 Nef to study immune modulation.HIV's evasion of the cellular immune response.Inhibition of human immunodeficiency virus type 1 by triciribine involves the accessory protein nefPathogenic conversion of live attenuated simian immunodeficiency virus vaccines is associated with expression of truncated NefNef-induced major histocompatibility complex class I down-regulation is functionally dissociated from its virion incorporation, enhancement of viral infectivity, and CD4 down-regulationThe intracytoplasmic domain of the Env transmembrane protein is a locus for attenuation of simian immunodeficiency virus SIVmac in rhesus macaques.Sequence variations in human immunodeficiency virus type 1 Nef are associated with different stages of disease.Human immunodeficiency virus type 1 Nef-induced CD4 cell surface downregulation is inhibited by ikarugamycinThe human thioesterase II protein binds to a site on HIV-1 Nef critical for CD4 down-regulation.Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression.Control of myeloid differentiation and survival by Stats.Expression of simian immunodeficiency virus nef in immune cells of transgenic mice leads to a severe AIDS-like disease.Cooperative interactions of simian immunodeficiency virus Nef, AP-2, and CD3-zeta mediate the selective induction of T-cell receptor-CD3 endocytosis.Nef increases the synthesis of and transports cholesterol to lipid rafts and HIV-1 progeny virions.Human immunodeficiency virus type 1 Nef domains required for disruption of major histocompatibility complex class I trafficking are also necessary for coprecipitation of Nef with HLA-A2.cis expression of the F12 human immunodeficiency virus (HIV) Nef allele transforms the highly productive NL4-3 HIV type 1 to a replication-defective strain: involvement of both Env gp41 and CD4 intracytoplasmic tails.Heat shock protein 40 is necessary for human immunodeficiency virus-1 Nef-mediated enhancement of viral gene expression and replication.HIV-1 Nef promotes survival of TF-1 macrophages by inducing Bcl-XL expression in an extracellular signal-regulated kinase-dependent manner.The effects of HIV-1 Nef on CD4 surface expression and viral infectivity in lymphoid cells are independent of rafts.Characterization and molecular basis of the oligomeric structure of HIV-1 nef protein.Sequence heterogeneity in human immunodeficiency virus type 1 nef in patients presenting with rapid progression and delayed progression to AIDS.
P2860
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P2860
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
HIV-1 Nef and host cell protein kinases.
@en
type
label
HIV-1 Nef and host cell protein kinases.
@en
prefLabel
HIV-1 Nef and host cell protein kinases.
@en
P356
P1476
HIV-1 Nef and host cell protein kinases.
@en
P2093
P304
P356
10.2741/A217
P577
1997-12-15T00:00:00Z