The minimal number of class II MHC-antigen complexes needed for T cell activation.
about
Ubiquitination of human leukocyte antigen (HLA)-DM by different membrane-associated RING-CH (MARCH) protein family E3 ligases targets different endocytic pathwaysHuman CD8+ T cells do not require the polarization of lipid rafts for activation and proliferationCell surface HLA-DR-invariant chain complexes are targeted to endosomes by rapid internalizationT cell recognition of weak ligands: roles of signaling, receptor number, and affinityProtective effect of the DNA vaccine encoding the major house dust mite allergens on allergic inflammation in the murine model of house dust mite allergy.MHC class II association with lipid rafts on the antigen presenting cell surfaceT cell antigen recognition at the cell membraneImmunoproteomics: Mass spectrometry-based methods to study the targets of the immune responseEfficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alphaCalcium response of helper T lymphocytes to antigen-presenting cells in a single-cell assay.Pillars article: Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry. Science 1992. 255: 1261-1263.Quantifying signaling-induced reorientation of T cell receptors during immunological synapse formation.T-cell antagonism by short half-life pMHC ligands can be mediated by an efficient trapping of T-cell polarization toward the APCClose encounters of the first and second kind: T-DC and T-B interactions in the lymph node.Predicting lymph node output efficiency using systems biology.Mapping the sensitivity of T cells with an optical trap: polarity and minimal number of receptors for Ca(2+) signalingClass II MHC self-antigen presentation in human B and T lymphocytesT cells in mice expressing a transgenic human TCR beta chain get positively selected but cannot be activated in the periphery by signaling through TCR.T-cell artificial focal triggering tools: linking surface interactions with cell response.Function-specific variations in the immunological synapses formed by cytotoxic T cells.Manipulating antigenic ligand strength to selectively target myelin-reactive CD4+ T cells in EAE.Gamma interferon can prevent herpes simplex virus type 1 reactivation from latency in sensory neurons.Paradoxical intrathymic positive selection in mice with only a covalently presented agonist peptideMultiple mechanisms allow Mycobacterium tuberculosis to continuously inhibit MHC class II-mediated antigen presentation by macrophages.Formation of supramolecular activation clusters on fresh ex vivo CD8+ T cells after engagement of the T cell antigen receptor and CD8 by antigen-presenting cells.Dissociation of peripheral T cell responses from thymocyte negative selection by weak agonists supports a spare receptor model of T cell activation.The (YXXL/I)2 signalling motif found in the cytoplasmic segments of the bovine leukaemia virus envelope protein and Epstein-Barr virus latent membrane protein 2A can elicit early and late lymphocyte activation events.Rapid formation of extended processes and engagement of Theiler's virus-infected neurons by CNS-infiltrating CD8 T cells.Autoimmune myocarditis induced in mice by cardiac C-protein. Cloning of complementary DNA encoding murine cardiac C-protein and partial characterization of the antigenic peptides.Distinct MHC class II molecules are associated on the dendritic cell surface in cholesterol-dependent membrane microdomainsKinetic proofreading in T-cell receptor signal transduction.Imaging T-cell antigen recognition and comparing immunological and neuronal synapses.Influenza vaccine responses in older adults.CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics.Sedative drug modulates T-cell and lymphocyte function-associated antigen-1 function.Cell adhesion and polarity during immune interactions.T-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters.Distinct mechanisms of immunosuppression as a consequence of major surgerySynthesis, stability, and subcellular distribution of major histocompatibility complex class II molecules in Langerhans cells infected with Leishmania major.T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node.
P2860
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P2860
The minimal number of class II MHC-antigen complexes needed for T cell activation.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
The minimal number of class II MHC-antigen complexes needed for T cell activation.
@en
type
label
The minimal number of class II MHC-antigen complexes needed for T cell activation.
@en
prefLabel
The minimal number of class II MHC-antigen complexes needed for T cell activation.
@en
P2093
P356
P1433
P1476
The minimal number of class II MHC-antigen complexes needed for T cell activation.
@en
P2093
P304
P356
10.1126/SCIENCE.2118680
P407
P577
1990-08-01T00:00:00Z