Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation.
about
Ubiquitination of human leukocyte antigen (HLA)-DM by different membrane-associated RING-CH (MARCH) protein family E3 ligases targets different endocytic pathwaysHuman CD8+ T cells do not require the polarization of lipid rafts for activation and proliferationCell surface HLA-DR-invariant chain complexes are targeted to endosomes by rapid internalizationT cell recognition of weak ligands: roles of signaling, receptor number, and affinitySyk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complexMHC class II association with lipid rafts on the antigen presenting cell surfaceT cell antigen recognition at the cell membraneImmunoproteomics: Mass spectrometry-based methods to study the targets of the immune responseEfficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alphaCalcium response of helper T lymphocytes to antigen-presenting cells in a single-cell assay.Quantifying signaling-induced reorientation of T cell receptors during immunological synapse formation.Low T cell receptor expression and thermal fluctuations contribute to formation of dynamic multifocal synapses in thymocytes.Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC moleculesT-cell antagonism by short half-life pMHC ligands can be mediated by an efficient trapping of T-cell polarization toward the APCClose encounters of the first and second kind: T-DC and T-B interactions in the lymph node.Mapping the sensitivity of T cells with an optical trap: polarity and minimal number of receptors for Ca(2+) signalingClass II MHC self-antigen presentation in human B and T lymphocytesT cells in mice expressing a transgenic human TCR beta chain get positively selected but cannot be activated in the periphery by signaling through TCR.Effects of intracellular calcium and actin cytoskeleton on TCR mobility measured by fluorescence recovery.T-cell artificial focal triggering tools: linking surface interactions with cell response.Expression of herpes simplex virus ICP47 and human cytomegalovirus US11 prevents recognition of transgene products by CD8(+) cytotoxic T lymphocytes.Mechanisms and consequences of peptide selection by the I-Ak class II molecule.Manipulating antigenic ligand strength to selectively target myelin-reactive CD4+ T cells in EAE.Herpes simplex virus infection of human fibroblasts and keratinocytes inhibits recognition by cloned CD8+ cytotoxic T lymphocytes.Paradoxical intrathymic positive selection in mice with only a covalently presented agonist peptideFormation of supramolecular activation clusters on fresh ex vivo CD8+ T cells after engagement of the T cell antigen receptor and CD8 by antigen-presenting cells.Dissociation of peripheral T cell responses from thymocyte negative selection by weak agonists supports a spare receptor model of T cell activation.Rapid formation of extended processes and engagement of Theiler's virus-infected neurons by CNS-infiltrating CD8 T cells.Autoimmune myocarditis induced in mice by cardiac C-protein. Cloning of complementary DNA encoding murine cardiac C-protein and partial characterization of the antigenic peptides.Distinct MHC class II molecules are associated on the dendritic cell surface in cholesterol-dependent membrane microdomainsKinetic proofreading in T-cell receptor signal transduction.Imaging T-cell antigen recognition and comparing immunological and neuronal synapses.Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.Self-pMHCII complexes are variably expressed in the thymus and periphery independent of mRNA expression but dependent on the activation state of the APCsMolecular properties of HLA-DQ alleles conferring susceptibility to or protection from insulin-dependent diabetes mellitus: keys to the fate of islet beta-cells.Sedative drug modulates T-cell and lymphocyte function-associated antigen-1 function.Perspective on antigen processing and presentation.Cell adhesion and polarity during immune interactions.T-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters.Suppression of human glioma xenografts with second-generation IL13R-specific chimeric antigen receptor-modified T cells.
P2860
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P2860
Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Quantitation of antigen-presen ...... essary for T-cell stimulation.
@en
type
label
Quantitation of antigen-presen ...... essary for T-cell stimulation.
@en
prefLabel
Quantitation of antigen-presen ...... essary for T-cell stimulation.
@en
P356
P1433
P1476
Quantitation of antigen-presen ...... essary for T-cell stimulation.
@en
P2093
P2888
P304
P356
10.1038/346574A0
P407
P577
1990-08-01T00:00:00Z
P6179
1043246091