Spinal PKC activity and expression: role in tolerance produced by continuous spinal morphine infusion.
about
mTOR, a new potential target for chronic pain and opioid-induced tolerance and hyperalgesiaIncreased response to morphine in mice lacking protein kinase C epsilonProteomic analysis of PKCγ-related proteins in the spinal cord of morphine-tolerant ratsResveratrol Enhances Neuroplastic Changes, Including Hippocampal Neurogenesis, and Memory in Balb/C Mice at Six Months of AgeOpioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance and hyperalgesiaThe effect of protein kinase C and G protein-coupled receptor kinase inhibition on tolerance induced by mu-opioid agonists of different efficacySpinal mediators that may contribute selectively to antinociceptive tolerance but not other effects of morphine as revealed by deletion of GluR5Therapeutic potential of PKC inhibitors in painful diabetic neuropathy.Protein kinase C-mediated phosphorylation of the μ-opioid receptor and its effects on receptor signaling.The neurobiology of opiate tolerance, dependence and sensitization: mechanisms of NMDA receptor-dependent synaptic plasticity.Role of kappa and delta opioid receptors in mediating morphine-induced antinociception in morphine-tolerant infant rats.Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance.Resistance to morphine analgesic tolerance in rats with deleted transient receptor potential vanilloid type 1-expressing sensory neurons.Involvement of protein kinase C in morphine tolerance at spinal levels of rats.Chronic opioid potentiates presynaptic but impairs postsynaptic N-methyl-D-aspartic acid receptor activity in spinal cords: implications for opioid hyperalgesia and tolerance.Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Protein kinase C in pain: involvement of multiple isoformsEvidence for an important role of protein phosphatases in the mechanism of morphine tolerancePersistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons.Psychiatric research: psychoproteomics, degradomics and systems biology.Pre-treatment with a PKC or PKA inhibitor prevents the development of morphine tolerance but not physical dependence in mice.Mu opioids and their receptors: evolution of a concept.An integrated quantitative proteomics and systems biology approach to explore synaptic protein profile changes during morphine exposure.Regulation of ERK1/2 phosphorylation by acute and chronic morphine - implications for the role of cAMP-responsive element binding factor (CREB)-dependent and Ets-like protein-1 (Elk-1)-dependent transcription; small interfering RNA-based strategy.Role of protein kinase C and mu-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons.Activation of protein kinase C in the spinal cord produces mechanical hyperalgesia by activating glutamate receptors, but does not mediate chronic muscle-induced hyperalgesia.BiP, an endoplasmic reticulum chaperone, modulates the development of morphine antinociceptive tolerance.Group I metabotropic glutamate receptors control metaplasticity of spinal cord learning through a protein kinase C-dependent mechanismSpinal amino acid release and repeated withdrawal in spinal morphine tolerant rats.Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization.Inhibition of β-ARK1 Ameliorates Morphine-induced Tolerance and Hyperalgesia Via Modulating the Activity of Spinal NMDA Receptors.In vitro and in vivo characterisation of the bifunctional MOP/DOP ligand UFP-505.
P2860
Q28081540-29AB5285-2DA9-4BE2-8327-CE6F4E126550Q28256829-553B76A6-F4AA-4F5D-8F76-A7E289ED88FBQ28481707-E4F288F8-C2E1-4677-93C3-06CBA10E38A8Q28551780-5C26E128-928C-4E0D-8F3D-5C91BA1FE37DQ28576512-B2C0BBDF-D4C7-43D2-86CF-CC520E3A5077Q33714922-F85C15D4-37E9-42B7-B5D2-2996D0122FE2Q33976800-F12DB84D-E936-4C45-B176-A0ED5E70C0FDQ34481699-B83F9225-B8C0-4ECB-8BAB-921A4D091427Q34715589-1593CC9B-CD03-462E-862F-D9A85741F569Q35164063-BB02CA80-7C2B-4DD4-9B88-E08B2C4E1B0AQ35173736-6438FBDF-E604-41B4-A950-03DBE6FEB578Q35264421-1CBF25EF-034F-4AD9-98C7-4057B73E3CC8Q35754296-3D373C0E-57E3-4AED-973F-36373C973AD9Q36012339-C12B383A-3BCA-4E42-BEA5-9950452E6BB3Q36127120-0228513F-9DBF-4778-95B6-F844E3187FDBQ36591603-DB873AF4-88F2-4F29-9E36-D77C288FD3C9Q36840305-F0DB80C3-7D7A-40C8-87EA-FAFD60DAD174Q37077450-744B09DD-2763-4561-9D88-7A9030F671BCQ37148281-50F71D7E-96E1-4AB9-86B0-A70AA290B5A6Q37157851-EFC16C19-7D03-43B2-96BD-6307AD84ACBEQ37172821-EB70F3B4-FB1B-4F43-A6FA-23E29B86955BQ37236111-09E37847-25F7-4C97-9140-10CC7C6EE6FBQ38138785-CD6B0449-85E8-4C6B-BF22-705C6656C265Q39963045-E2063D4A-2025-423A-8501-E5A1B4B89D94Q41531803-E761E377-F171-4256-9133-E948EE175C15Q41677380-FD540C72-A353-40F1-B82A-D5B66CCAFF9AQ41810923-57C6D0A8-1F20-437E-8F24-0474E352653FQ42125977-B3DBDF1C-97AC-4EF6-8EB7-215F154EE7A7Q43263513-DF54245B-1923-4193-A95C-BC3B59EF3F1AQ45108443-6056B410-9AFE-4B8B-8E92-BE7CCE10DF63Q47702437-921F3EC1-6E6B-46D8-BA46-E9BE3477BFDDQ51741932-A07504A5-BA80-4A06-A304-791F82508ABE
P2860
Spinal PKC activity and expression: role in tolerance produced by continuous spinal morphine infusion.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Spinal PKC activity and expres ...... uous spinal morphine infusion.
@en
type
label
Spinal PKC activity and expres ...... uous spinal morphine infusion.
@en
prefLabel
Spinal PKC activity and expres ...... uous spinal morphine infusion.
@en
P2093
P1433
P1476
Spinal PKC activity and expres ...... uous spinal morphine infusion.
@en
P2093
P304
P356
10.1016/S0304-3959(99)00281-X
P407
P577
2000-04-01T00:00:00Z