Pre-treatment with a PKC or PKA inhibitor prevents the development of morphine tolerance but not physical dependence in mice.
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Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization.Contribution of adenylyl cyclase modulation of pre- and postsynaptic GABA neurotransmission to morphine antinociception and tolerance.Intracerebroventricular opiate infusion for refractory head and facial painActivation of protein kinase C (PKC)α or PKCε as an approach to increase morphine tolerance in respiratory depression and lethal overdoseThe role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics.Intrathecal PKA-selective siRNA treatment blocks sustained morphine-mediated pain sensitization and antinociceptive tolerance in ratsFunctional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance.Involvement of protein kinase C in morphine tolerance at spinal levels of rats.Morphine Tolerance and Physical Dependence Are Altered in Conditional HIV-1 Tat Transgenic Mice.Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Reversal of morphine analgesic tolerance by ethanol in the mouse.6β-N-Heterocyclic Substituted Naltrexamine Derivative BNAP: A Peripherally Selective Mixed MOR/KOR Ligand.Opioid receptor trafficking and signaling: what happens after opioid receptor activation?Spider peptide Phα1β induces analgesic effect in a model of cancer pain.Hyperbaric oxygen treatment suppresses withdrawal signs in morphine-dependent mice.Protein kinase C phosphorylates the cAMP response element binding protein in the hypothalamic paraventricular nucleus during morphine withdrawal.Effect of the methanolic extracts of different parts of Ferula assa-foetida on naloxone-induced withdrawal behavior in morphine-dependent mice.Aquaporin 4 Forms a Macromolecular Complex with Glutamate Transporter 1 and Mu Opioid Receptor in Astrocytes and Participates in Morphine Dependence.
P2860
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P2860
Pre-treatment with a PKC or PKA inhibitor prevents the development of morphine tolerance but not physical dependence in mice.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 24 April 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Pre-treatment with a PKC or PK ...... t physical dependence in mice.
@en
Pre-treatment with a PKC or PK ...... t physical dependence in mice.
@nl
type
label
Pre-treatment with a PKC or PK ...... t physical dependence in mice.
@en
Pre-treatment with a PKC or PK ...... t physical dependence in mice.
@nl
prefLabel
Pre-treatment with a PKC or PK ...... t physical dependence in mice.
@en
Pre-treatment with a PKC or PK ...... t physical dependence in mice.
@nl
P2093
P2860
P1433
P1476
Pre-treatment with a PKC or PK ...... t physical dependence in mice.
@en
P2093
Bichoy H Gabra
Chris P Bailey
Eamonn Kelly
Forrest L Smith
Graeme Henderson
William L Dewey
P2860
P356
10.1016/J.BRAINRES.2008.04.036
P407
P577
2008-04-24T00:00:00Z