Role of protein kinase C and mu-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons.
about
Role of FK506 binding protein 12 in morphine-induced μ-opioid receptor internalization and desensitization.Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization.μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization.Identification of phosphorylation sites in the COOH-terminal tail of the μ-opioid receptorProtein kinase C-mediated phosphorylation of the μ-opioid receptor and its effects on receptor signaling.μ-Opioid receptor activation and noradrenaline transport inhibition by tapentadol in rat single locus coeruleus neuronsFunctional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance.Tolerance to the antinociceptive effects of chronic morphine requires c-Jun N-terminal kinase.Mu opioid receptor stimulation activates c-Jun N-terminal kinase 2 by distinct arrestin-dependent and independent mechanisms.Role of G Protein-Coupled Receptor Kinases 2 and 3 in μ-Opioid Receptor Desensitization and InternalizationInvolvement of protein kinase C in morphine tolerance at spinal levels of rats.Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons.Endomorphin-2: a biased agonist at the μ-opioid receptor.Ethanol Reversal of Tolerance to the Respiratory Depressant Effects of MorphineMorphine desensitization and cellular tolerance are distinguished in rat locus ceruleus neurons.Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Tolerance to the antinociceptive and hypothermic effects of morphine is mediated by multiple isoforms of c-Jun N-terminal kinase.Increased agonist affinity at the μ-opioid receptor induced by prolonged agonist exposure.Ethanol reversal of cellular tolerance to morphine in rat locus coeruleus neuronsFK506-binding protein 12 modulates μ-opioid receptor phosphorylation and protein kinase C(ε)-dependent signaling by its direct interaction with the receptor.Involvement of PKC alpha and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of mu-opioid receptors in mature brain neurons.Blockade of neuronal dopamine D2 receptor attenuates morphine tolerance in mice spinal cord.Morphine-induced trafficking of a mu-opioid receptor interacting protein in rat locus coeruleus neurons.Heterologous regulation of agonist-independent μ-opioid receptor phosphorylation by protein kinase COpioid receptor trafficking and signaling: what happens after opioid receptor activation?Efficacy and ligand bias at the μ-opioid receptor.Different mechanisms of homologous and heterologous μ-opioid receptor phosphorylation.The μ-opioid receptor: an electrophysiologist's perspective from the sharp end.Involvement of kappa opioid receptors in the formalin-induced inhibition of analgesic tolerance to morphine via suppression of conventional protein kinase C activation.The subtleties of µ-opioid receptor phosphorylation.Morphine-induced internalization of the L83I mutant of the rat μ-opioid receptorRecovery from mu-opioid receptor desensitization after chronic treatment with morphine and methadone.The opioid receptor pharmacology of GSK1521498 compared to other ligands with differential effects on compulsive reward-related behaviours.Analgesic tolerance to morphine is regulated by PPARγ.A continuous, fluorescence-based assay of μ-opioid receptor activation in AtT-20 cells.Effect of Tamoxifen and Brain-Penetrant Protein Kinase C and c-Jun N-Terminal Kinase Inhibitors on Tolerance to Opioid-Induced Respiratory Depression in Mice.Desensitization and tolerance of mu opioid receptors on pontine Kolliker-Fuse neurons.Oxycodone-induced tolerance to respiratory depression: reversal by ethanol, pregabalin and protein kinase C inhibition.Yokukansan (Kampo medicinal formula) prevents the development of morphine tolerance by inhibiting the secretion of orexin A.
P2860
Q33568279-5BE1F4A9-A629-4A7F-826D-564D18C91B9AQ33708526-7688D0DC-9215-42EF-ADDE-A4FB02DB5633Q34310081-3C3F53EF-7798-4180-B57B-387A7C1E3DAEQ34482298-CFF216BA-D027-4293-8C21-8799FEFEA6C7Q34715589-F9B85FE2-306B-4578-B98E-03A0B6FC3D3AQ34939720-9E3D3A1B-3F66-4682-BBBE-919A51EF95D8Q35264421-3A1F9EE2-FBB7-4267-A553-76D5FE00D068Q35736611-303D5B5C-5C74-44AC-98A5-AB0E9CDF3E79Q35822876-BAC98AA5-DB5C-44F2-8E47-B77D9227BF6AQ35897872-499965D5-0BD1-42FF-95CE-9AA947902572Q36012339-CDBB0A97-393C-4B7A-9EDF-DAADD6207868Q36025329-3408F540-A18F-4C48-93C1-D3CAAE58798DQ36105495-B470CE2F-17A0-4C3A-8447-AED256CA6D95Q36174854-A684F4A2-6137-4607-B5C0-9BEDCAF70F26Q36335620-FD0FB3DB-D089-416E-9501-2A450E2EF6D7Q36591603-F9A43452-DE47-43E5-B1ED-9CAAC1BD5499Q36730465-6AB601B6-0A96-4DCB-9C1A-1140A8371395Q37014120-99968A80-A3DA-416B-A4B4-BE6B24835D61Q37027080-08F3A54D-BAE3-42CF-B6A9-87EE82695095Q37405419-5D6BBB64-93DF-4272-B5CA-1B3BC6A4BA0BQ37481307-732AFF50-BA46-4F34-A8EB-BC026E9A56FCQ37526133-691F0DC3-1A77-45E5-984A-8B66688E68BCQ37592198-42030B20-4601-4E6A-B986-81A0356F500AQ37635282-C229D83C-740A-4C1B-B563-10DB49DF0749Q37938862-7165C713-E32E-4867-A3BA-8579129F5E51Q38104365-11CD2782-2D29-4F0A-93A3-9545AEB9BD58Q38187199-AE5BDE78-39E1-4E49-899E-85E832DDA7EFQ38196854-CC779A85-DE15-49F1-A734-81264D3AA593Q38342129-34155935-FA24-4911-9D3C-9A717B8BD15CQ38464911-18FBD05E-B647-413C-8875-6230331052BCQ41823097-28D538FD-D5F9-407E-8FD7-9272FF7E9FA5Q41891627-89051E1B-628D-438E-95BE-2782F3BE730EQ42090559-72BCCF05-469D-47F0-9CF1-BF249765C83DQ43105759-507BBB2F-1A58-41B9-B719-F51620AADAF0Q44336146-8BA3A7FE-9240-421C-86AE-16517F5C8EAEQ44342944-4EE10F26-EAE6-438E-8266-585CAF459D04Q44350406-E902BC16-DB1A-4E40-9B4B-32D3A0FEF2EFQ54119525-0E5DCAD0-5D05-4C3E-95A4-3BAF1678C479Q55510298-E3C3ADCF-E27D-4BC3-A0DA-6E8800484E77
P2860
Role of protein kinase C and mu-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Role of protein kinase C and m ...... n rat locus coeruleus neurons.
@en
type
label
Role of protein kinase C and m ...... n rat locus coeruleus neurons.
@en
prefLabel
Role of protein kinase C and m ...... n rat locus coeruleus neurons.
@en
P2093
P2860
P1476
Role of protein kinase C and m ...... in rat locus coeruleus neurons
@en
P2093
P2860
P304
P356
10.1111/J.1460-9568.2008.06573.X
P407
P50
P577
2009-01-01T00:00:00Z