PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis.
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Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxisMoving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytesThe role of phosphoinositide-regulated actin reorganization in chemotaxis and cell migrationSynthetic activation of endogenous PI3K and Rac identifies an AND-gate switch for cell polarization and migrationAsymmetrical macromolecular complex formation of lysophosphatidic acid receptor 2 (LPA2) mediates gradient sensing in fibroblasts.Interaction of motility, directional sensing, and polarity modules recreates the behaviors of chemotaxing cellsPolarization of migrating monocytic cells is independent of PI 3-kinase activityA model for a correlated random walk based on the ordered extension of pseudopodiaNavigation of chemotactic cells by parallel signaling to pseudopod persistence and orientationGβ Regulates Coupling between Actin Oscillators for Cell Polarity and Directional MigrationThe ordered extension of pseudopodia by amoeboid cells in the absence of external cuesNeutrophils establish rapid and robust WAVE complex polarity in an actin-dependent fashion.Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide bindingFrom Physics to Pharmacology?Random versus directionally persistent cell migrationSignaling networks that regulate cell migrationSpontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblastsEssential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxisPhospholipase C regulation of phosphatidylinositol 3,4,5-trisphosphate-mediated chemotaxis.Four key signaling pathways mediating chemotaxis in Dictyostelium discoideum.Switching direction in electric-signal-induced cell migration by cyclic guanosine monophosphate and phosphatidylinositol signalingPhosphoinositide-dependent protein kinase (PDK) activity regulates phosphatidylinositol 3,4,5-trisphosphate-dependent and -independent protein kinase B activation and chemotaxisA Rap/phosphatidylinositol 3-kinase pathway controls pseudopod formation [corrected].Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.Disruption of PKB signaling restores polarity to cells lacking tumor suppressor PTEN.Mammalian target of rapamycin and Rictor control neutrophil chemotaxis by regulating Rac/Cdc42 activity and the actin cytoskeletonAn excitable signal integrator couples to an idling cytoskeletal oscillator to drive cell migration.Bleb-driven chemotaxis of Dictyostelium cells.Group choreography: mechanisms orchestrating the collective movement of border cellsModeling cellular deformations using the level set formalismDifferentiation-inducing factor-1 and -2 function also as modulators for Dictyostelium chemotaxis.Food searching strategy of amoeboid cells by starvation induced run length extensionDifferential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafishMoving in the right direction: how eukaryotic cells migrate along chemical gradients.Proteomic identification of phosphatidylinositol (3,4,5) triphosphate-binding proteins in Dictyostelium discoideum.The role of ADP-ribosylation in regulating DNA double-strand break repairCellular responses to extracellular guidance cuesThe signaling mechanisms underlying cell polarity and chemotaxisFGFR1-induced epithelial to mesenchymal transition through MAPK/PLCγ/COX-2-mediated mechanisms.Nhe1 is essential for potassium but not calcium facilitation of cell motility and the monovalent cation requirement for chemotactic orientation in Dictyostelium discoideum
P2860
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P2860
PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis.
@en
type
label
PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis.
@en
prefLabel
PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis.
@en
P2093
P2860
P1433
P1476
PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis.
@en
P2093
Lingfeng Chen
Mark A Landree
Miho Iijima
Pablo A Iglesias
Peter N Devreotes
Yi Elaine Huang
Yuan Xiong
P2860
P304
P356
10.1016/J.DEVCEL.2007.03.005
P407
P577
2007-04-01T00:00:00Z