PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis. - Wikidata - awgldk - TriplyDB

PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis.

PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis.

http://www.wikidata.org/entity/Q41748825

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Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxis Moving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytes The role of phosphoinositide-regulated actin reorganization in chemotaxis and cell migration Synthetic activation of endogenous PI3K and Rac identifies an AND-gate switch for cell polarization and migration Asymmetrical macromolecular complex formation of lysophosphatidic acid receptor 2 (LPA2) mediates gradient sensing in fibroblasts.Interaction of motility, directional sensing, and polarity modules recreates the behaviors of chemotaxing cells Polarization of migrating monocytic cells is independent of PI 3-kinase activity A model for a correlated random walk based on the ordered extension of pseudopodia Navigation of chemotactic cells by parallel signaling to pseudopod persistence and orientation Gβ Regulates Coupling between Actin Oscillators for Cell Polarity and Directional Migration The ordered extension of pseudopodia by amoeboid cells in the absence of external cues Neutrophils establish rapid and robust WAVE complex polarity in an actin-dependent fashion.Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding From Physics to Pharmacology?Random versus directionally persistent cell migration Signaling networks that regulate cell migration Spontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblasts Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxis Phospholipase C regulation of phosphatidylinositol 3,4,5-trisphosphate-mediated chemotaxis.Four key signaling pathways mediating chemotaxis in Dictyostelium discoideum.Switching direction in electric-signal-induced cell migration by cyclic guanosine monophosphate and phosphatidylinositol signaling Phosphoinositide-dependent protein kinase (PDK) activity regulates phosphatidylinositol 3,4,5-trisphosphate-dependent and -independent protein kinase B activation and chemotaxis A Rap/phosphatidylinositol 3-kinase pathway controls pseudopod formation [corrected].Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.Disruption of PKB signaling restores polarity to cells lacking tumor suppressor PTEN.Mammalian target of rapamycin and Rictor control neutrophil chemotaxis by regulating Rac/Cdc42 activity and the actin cytoskeleton An excitable signal integrator couples to an idling cytoskeletal oscillator to drive cell migration.Bleb-driven chemotaxis of Dictyostelium cells.Group choreography: mechanisms orchestrating the collective movement of border cells Modeling cellular deformations using the level set formalism Differentiation-inducing factor-1 and -2 function also as modulators for Dictyostelium chemotaxis.Food searching strategy of amoeboid cells by starvation induced run length extension Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish Moving in the right direction: how eukaryotic cells migrate along chemical gradients.Proteomic identification of phosphatidylinositol (3,4,5) triphosphate-binding proteins in Dictyostelium discoideum.The role of ADP-ribosylation in regulating DNA double-strand break repair Cellular responses to extracellular guidance cues The signaling mechanisms underlying cell polarity and chemotaxis FGFR1-induced epithelial to mesenchymal transition through MAPK/PLCγ/COX-2-mediated mechanisms.Nhe1 is essential for potassium but not calcium facilitation of cell motility and the monovalent cation requirement for chemotactic orientation in Dictyostelium discoideum

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P2860

PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis.

http://www.wikidata.org/entity/Q41748825

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PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis.

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J.DEVCEL.2007.03.005

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Developmental Cell

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PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis.

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Lingfeng Chen

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Mark A Landree

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Miho Iijima

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Ming Tang

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Pablo A Iglesias

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Peter N Devreotes

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Yi Elaine Huang

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Yuan Xiong

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P2860

Mechanism of action and in vivo role of platelet-derived growth factor

The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients

A cell's sense of direction

CXCR3-mediated chemotaxis of human T cells is regulated by a Gi- and phospholipase C-dependent pathway and not via activation of MEK/p44/p42 MAPK nor Akt/PI-3 kinase

Novel mechanism of PTEN regulation by its phosphatidylinositol 4,5-bisphosphate binding motif is critical for chemotaxis

Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis

Distinct roles of PI(3,4,5)P3 during chemoattractant signaling in Dictyostelium: a quantitative in vivo analysis by inhibition of PI3-kinase.

Live imaging of wound inflammation in Drosophila embryos reveals key roles for small GTPases during in vivo cell migration

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