Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1.
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Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complexFunctional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesisThe Renaissance or the cuckoo clockStructure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding SurfaceStructural analysis of human Cdc20 supports multisite degron recognition by APC/CElectron microscopy structure of human APC/CCDH1–EMI1 reveals multimodal mechanism of E3 ligase shutdownThe APC/C subunit Mnd2/Apc15 promotes Cdc20 autoubiquitination and spindle assembly checkpoint inactivation.Spatiotemporal regulation of the anaphase-promoting complex in mitosisExperimental validation of Ankrd17 and Anapc10, two novel meiotic genes predicted by computational models in miceMicrotubule-dependent regulation of mitotic protein degradation.Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.Molecular architecture and mechanism of the anaphase-promoting complexActivation of the APC/C ubiquitin ligase by enhanced E2 efficiencySNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs.The Cdc20-binding Phe box of the spindle checkpoint protein BubR1 maintains the mitotic checkpoint complex during mitosis.The biochemistry of mitosisRING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complexMutual regulation between the spindle checkpoint and APC/C.An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitinationRegulation of E2F1 by APC/C Cdh1 via K11 linkage-specific ubiquitin chain formation.Dephosphorylation of Cdc20 is required for its C-box-dependent activation of the APC/CMad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregationControl of APC/C-dependent ubiquitin chain elongation by reversible phosphorylationState of the APC/C: organization, function, and structure.Mechanism of APC/CCDC20 activation by mitotic phosphorylation.Mutually dependent degradation of Ama1p and Cdc20p terminates APC/C ubiquitin ligase activity at the completion of meiotic development in yeast.Substrate Recognition by the Cdh1 Destruction Box Receptor Is a General Requirement for APC/CCdh1-mediated ProteolysisProcessive ubiquitin chain formation by the anaphase-promoting complex.Structural insights into anaphase-promoting complex function and mechanism.Panta rhei: the APC/C at steady state.Flipping the switch from g1 to s phase with e3 ubiquitin ligasesControl the host cell cycle: viral regulation of the anaphase-promoting complex.Assays to Monitor Autophagy in Saccharomyces cerevisiaeThe Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation.Building a Regulatory Network with Short Linear Sequence Motifs: Lessons from the Degrons of the Anaphase-Promoting Complex.Recombinant expression, reconstitution and structure of human anaphase-promoting complex (APC/C).Cdc20 control of cell fate during prolonged mitotic arrest: do Cdc20 protein levels affect cell fate in response to antimitotic compounds?BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner.Structure of an APC3-APC16 complex: insights into assembly of the anaphase-promoting complex/cyclosome.The mitotic checkpoint complex (MCC): looking back and forth after 15 years.
P2860
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P248
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P2860
Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Substrate binding on the APC/C ...... the processivity factor Doc1.
@en
type
label
Substrate binding on the APC/C ...... the processivity factor Doc1.
@en
prefLabel
Substrate binding on the APC/C ...... the processivity factor Doc1.
@en
P2093
P2860
P356
P1476
Substrate binding on the APC/C ...... d the processivity factor Doc1
@en
P2093
Bettina A Buschhorn
Franz Herzog
Holger Stark
Jan-Michael Peters
Marta Galova
Prakash Dube
P2860
P2888
P356
10.1038/NSMB.1979
P577
2010-12-26T00:00:00Z