A novel and comprehensive synthetic approach for the elucidation of protein antigenic structures. Determination of the full antigenic profile of the alpha-chain of human haemoglobin.
about
Human autoantibodies reactive with synthetic autoantigens from T-cell receptor beta chain.Exquisite specificity and peptide epitope recognition promiscuity, properties shared by antibodies from sharks to humans.T cells specific for alpha-beta interface regions of hemoglobin recognize the isolated subunit but not the tetramer and indicate presentation without processing.Molecular characterization of human Ro/SS-A antigen. Amino terminal sequence of the protein moiety of human Ro/SS-A antigen and immunological activity of a corresponding synthetic peptideProfile of the continuous antigenic regions on the extracellular part of the alpha chain of an acetylcholine receptor.Structural, antigenic and evolutionary analyses of immunoglobulins and T cell receptors.Basic immunological aspects of botulinum toxin therapy.Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid.Localization and synthesis of the hormone-binding regions of the human thyrotropin receptor.Immunological detection of hemoglobin in bones of ancient Roman times and of Iron and Eneolithic AgesAntigenic structures of proteins. Their determination has revealed important aspects of immune recognition and generated strategies for synthetic mimicking of protein binding sites.Autoimmune T cell recognition of human acetylcholine receptor: the sites of T cell recognition in myasthenia gravis on the extracellular part of the alpha subunit.Mapping of the full profile of T cell allorecognition regions on HLA-DR2 beta subunit.Profile of the alpha-bungarotoxin-binding regions on the extracellular part of the alpha-chain of Torpedo californica acetylcholine receptor.Localization and synthesis of the acetylcholine-binding site in the alpha-chain of the Torpedo californica acetylcholine receptor.Surface-simulation synthesis of the substrate-binding site of an enzyme. Demonstration with trypsinHaemoglobin binding with haptoglobin. Localization of the haptoglobin-binding sites on the beta-chain of human haemoglobin by synthetic overlapping peptides encompassing the entire chain.The short-neurotoxin-binding regions on the alpha-chain of human and Torpedo californica acetylcholine receptorsConformation-dependent recognition of a protein by T cells requires presentation without processing.Site recognition by protein-primed T cells shows a non-specific peptide size requirement beyond the essential residues of the site. Demonstration by defining an immunodominant T site in myoglobin.T-cell recognition of human haemoglobin. Localization of the full T-cell recognition profile of the beta-chain by a comprehensive synthetic strategyAntigenic structure of human haemoglobin. Localization of the antigenic sites of the beta-chain in three host species by synthetic overlapping peptides representing the entire chainStructurally inherent antigenic sites. Localization of the antigenic sites of the alpha-chain of human haemoglobin in three host species by a comprehensive synthetic approach.Haemoglobin binding with haptoglobin. Localization of the haptoglobin-binding site on the alpha-chain of human haemoglobin.Characteristics of peptides which compete for presented antigen-binding sites on antigen-presenting cells.Immune recognition of human major histocompatibility antigens: localization by a comprehensive synthetic strategy of the continuous antigenic sites in the first domain of HLA-DR2 beta chain.
P2860
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P2860
A novel and comprehensive synthetic approach for the elucidation of protein antigenic structures. Determination of the full antigenic profile of the alpha-chain of human haemoglobin.
description
1980 nî lūn-bûn
@nan
1980年の論文
@ja
1980年論文
@yue
1980年論文
@zh-hant
1980年論文
@zh-hk
1980年論文
@zh-mo
1980年論文
@zh-tw
1980年论文
@wuu
1980年论文
@zh
1980年论文
@zh-cn
name
A novel and comprehensive synt ...... ha-chain of human haemoglobin.
@en
type
label
A novel and comprehensive synt ...... ha-chain of human haemoglobin.
@en
prefLabel
A novel and comprehensive synt ...... ha-chain of human haemoglobin.
@en
P2860
P356
P1433
P1476
A novel and comprehensive synt ...... ha-chain of human haemoglobin.
@en
P2093
P2860
P304
P356
10.1042/BJ1910261
P407
P577
1980-10-01T00:00:00Z