Computation of electrostatic complements to proteins: a case of charge stabilized binding
about
The maximal affinity of ligandsCrystal structural analysis of protein-protein interactions drastically destabilized by a single mutationRandomization of the receptor alpha chain recruitment epitope reveals a functional interleukin-5 with charge depletion in the CD loop.Molecular recognition in a diverse set of protein-ligand interactions studied with molecular dynamics simulations and end-point free energy calculations.Enrichment of chemical libraries docked to protein conformational ensembles and application to aldehyde dehydrogenase 2Differences in electrostatic properties at antibody-antigen binding sites: implications for specificity and cross-reactivity.Profiling charge complementarity and selectivity for binding at the protein surface.Gradient Models in Molecular Biophysics: Progress, Challenges, Opportunities.Targeting multiple conformations leads to small molecule inhibitors of the uPAR·uPA protein-protein interaction that block cancer cell invasionBiophysical limits of protein-ligand binding.Electrostatic interactions in the GCN4 leucine zipper: substantial contributions arise from intramolecular interactions enhanced on bindingAccurate solution of multi-region continuum biomolecule electrostatic problems using the linearized Poisson-Boltzmann equation with curved boundary elements.A "Reverse-Schur" Approach to Optimization With Linear PDE Constraints: Application to Biomolecule Analysis and DesignCharge Optimization Theory for Induced-Fit Ligands.Optimization of binding electrostatics: charge complementarity in the barnase-barstar protein complex.Computational methods for biomolecular electrostatics.Exploring the molecular design of protein interaction sites with molecular dynamics simulations and free energy calculationsTales of Dihydrofolate Binding to R67 Dihydrofolate Reductase.Quantum mechanical studies of DNA and LNA.Dynamics of protein-protein encounter: a Langevin equation approach with reaction patches.How optimal are the binding energetics of barnase and barstar?The role of charged surface residues in the binding ability of small hubs in protein-protein interaction networksEnergy functions for protein design I: efficient and accurate continuum electrostatics and solvation.Identification of a functional site on the type I TGF-beta receptor by mutational analysis of its ectodomain.Role of Lys-32 residues in R67 dihydrofolate reductase probed by asymmetric mutations.Solvation energy density occlusion approximation for evaluation of desolvation penalties in biomolecular interactions.Evaluation of electrostatic interactions.
P2860
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P2860
Computation of electrostatic complements to proteins: a case of charge stabilized binding
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Computation of electrostatic complements to proteins: a case of charge stabilized binding
@en
type
label
Computation of electrostatic complements to proteins: a case of charge stabilized binding
@en
prefLabel
Computation of electrostatic complements to proteins: a case of charge stabilized binding
@en
P2093
P2860
P356
P1433
P1476
Computation of electrostatic complements to proteins: a case of charge stabilized binding
@en
P2093
P2860
P304
P356
10.1002/PRO.5560070122
P577
1998-01-01T00:00:00Z