Triheteromeric NR1/NR2A/NR2B receptors constitute the major N-methyl-D-aspartate receptor population in adult hippocampal synapses.
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NMDA receptor modulators: an updated patent review (2013-2014)Recent progress in understanding subtype specific regulation of NMDA receptors by G Protein Coupled Receptors (GPCRs)Molecular bases of NMDA receptor subtype-dependent propertiesComputational investigation of the changing patterns of subtype specific NMDA receptor activation during physiological glutamatergic neurotransmissionSurface dynamics of GluN2B-NMDA receptors controls plasticity of maturing glutamate synapsesAcoustic trauma slows AMPA receptor-mediated EPSCs in the auditory brainstem, reducing GluA4 subunit expression as a mechanism to rescue binaural functionZinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunitDynorphin up-regulation in the dentate granule cell mossy fiber pathway following chronic inhibition of GluN2B-containing NMDAR is associated with increased CREB (Ser 133) phosphorylation, but is independent of BDNF/TrkB signaling pathwaysNicotinic and muscarinic agonists and acetylcholinesterase inhibitors stimulate a common pathway to enhance GluN2B-NMDAR responses.Sensitivity of N-methyl-D-aspartate receptor-mediated excitatory postsynaptic potentials and synaptic plasticity to TCN 201 and TCN 213 in rat hippocampal slices.Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo.N-methyl-D-aspartate receptor mechanosensitivity is governed by C terminus of NR2B subunit.GluN2A-/- Mice Lack Bidirectional Synaptic Plasticity in the Dentate Gyrus and Perform Poorly on Spatial Pattern Separation TasksHydroxyproline-induced Helical Disruption in Conantokin Rl-B Affects Subunit-selective Antagonistic Activities toward Ion Channels of N-Methyl-d-aspartate Receptors.MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit.TCN 201 selectively blocks GluN2A-containing NMDARs in a GluN1 co-agonist dependent but non-competitive mannerThe subtype of GluN2 C-terminal domain determines the response to excitotoxic insults.Chronic opioid potentiates presynaptic but impairs postsynaptic N-methyl-D-aspartic acid receptor activity in spinal cords: implications for opioid hyperalgesia and tolerance.Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonistBi-directional regulation of CaMKIIα phosphorylation at Thr286 by NMDA receptors in cultured cortical neuronsOsmotic Edema Rapidly Increases Neuronal Excitability Through Activation of NMDA Receptor-Dependent Slow Inward Currents in Juvenile and Adult HippocampusCaMKII regulation in information processing and storage.NMDA receptors with incomplete Mg²⁺ block enable low-frequency transmission through the cerebellar cortex.Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling.Ghrelin receptor activity amplifies hippocampal N-methyl-d-aspartate receptor-mediated postsynaptic currents and increases phosphorylation of the GluN1 subunit at Ser896 and Ser897Increased NR2A:NR2B ratio compresses long-term depression range and constrains long-term memory.Diversity in NMDA receptor composition: many regulators, many consequences.Presynaptic GluN2D receptors detect glutamate spillover and regulate cerebellar GABA release.Metabotropic NMDA receptor function is required for β-amyloid-induced synaptic depression.Selective Pharmacological Modulation of Pyramidal Neurons and Interneurons in the CA1 Region of the Rat Hippocampus.The blockade of NMDA receptor ion channels by ketamine is enhanced in developing rat cortical neurons.Activated CaMKII couples GluN2B and casein kinase 2 to control synaptic NMDA receptors.Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway.Effects of sex and DTNBP1 (dysbindin) null gene mutation on the developmental GluN2B-GluN2A switch in the mouse cortex and hippocampus.Acute 5-HT7 receptor activation increases NMDA-evoked currents and differentially alters NMDA receptor subunit phosphorylation and trafficking in hippocampal neurons.Subunit-selective N-Methyl-d-aspartate (NMDA) Receptor Signaling through Brefeldin A-resistant Arf Guanine Nucleotide Exchange Factors BRAG1 and BRAG2 during Synapse Maturation.An increase in the association of GluN2B containing NMDA receptors with membrane scaffolding proteins was related to memory declines during agingAllosteric modulators for the treatment of schizophrenia: targeting glutamatergic networksGluN2A and GluN2B subunit-containing NMDA receptors in hippocampal plasticity.NMDA receptor as a newly identified member of the metabotropic glutamate receptor family: clinical implications for neurodegenerative diseases.
P2860
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P2860
Triheteromeric NR1/NR2A/NR2B receptors constitute the major N-methyl-D-aspartate receptor population in adult hippocampal synapses.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Triheteromeric NR1/NR2A/NR2B r ...... in adult hippocampal synapses.
@en
type
label
Triheteromeric NR1/NR2A/NR2B r ...... in adult hippocampal synapses.
@en
prefLabel
Triheteromeric NR1/NR2A/NR2B r ...... in adult hippocampal synapses.
@en
P2860
P356
P1476
Triheteromeric NR1/NR2A/NR2B r ...... in adult hippocampal synapses.
@en
P2093
Claudia Rauner
Georg Köhr
P2860
P304
P356
10.1074/JBC.M110.182600
P407
P577
2010-12-29T00:00:00Z