Efficient synthesis of simvastatin by use of whole-cell biocatalysis.
about
Directed Evolution and Structural Characterization of a Simvastatin SynthaseDifferent active-site loop orientation in serine hydrolases versus acyltransferasesCrystal structure and biochemical studies of the trans-acting polyketide enoyl reductase LovC from lovastatin biosynthesisThe role of distant mutations and allosteric regulation on LovD active site dynamicsImportance of microbial natural products and the need to revitalize their discovery.Engineered polyketide biosynthesis and biocatalysis in Escherichia coli.Rational improvement of simvastatin synthase solubility in Escherichia coli leads to higher whole-cell biocatalytic activity.Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products.LovG: the thioesterase required for dihydromonacolin L release and lovastatin nonaketide synthase turnover in lovastatin biosynthesis.Metabolic engineering is key to a sustainable chemical industry.Regioselective enzymatic acylation of complex natural products: expanding molecular diversity.Production of valuable compounds by molds and yeasts.Genome editing approaches: manipulating of lovastatin and taxol synthesis of filamentous fungi by CRISPR/Cas9 system.Comparative Study on Whole Genome Sequences of Aspergillus terreus (Soil Fungus) and Diaporthe ampelina (Endophytic Fungus) with Reference to Lovastatin Production.
P2860
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P2860
Efficient synthesis of simvastatin by use of whole-cell biocatalysis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Efficient synthesis of simvastatin by use of whole-cell biocatalysis.
@en
type
label
Efficient synthesis of simvastatin by use of whole-cell biocatalysis.
@en
prefLabel
Efficient synthesis of simvastatin by use of whole-cell biocatalysis.
@en
P2860
P356
P1476
Efficient synthesis of simvastatin by use of whole-cell biocatalysis.
@en
P2093
P2860
P304
P356
10.1128/AEM.02820-06
P407
P577
2007-02-02T00:00:00Z