SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans.
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Sumoylation in Synaptic Function and DysfunctionRole of Extracellular Vesicles and microRNAs on Dysfunctional Angiogenesis during Preeclamptic PregnanciesDeSUMOylation Controls Insulin Exocytosis in Response to Metabolic Signals.SUMOylation protects against IL-1β-induced apoptosis in INS-1 832/13 cells and human islets.Role of SUMO-specific protease 2 in reprogramming cellular glucose metabolism.Calcium current inactivation rather than pool depletion explains reduced exocytotic rate with prolonged stimulation in insulin-secreting INS-1 832/13 cells.Human islet function following 20 years of cryogenic biobanking.SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretionIn vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule traffickingIsocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cellsSUMOylation of pancreatic glucokinase regulates its cellular stability and activityControl of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion.Interleukin-1 signaling contributes to acute islet compensationSenp2 expression was induced by chronic glucose stimulation in INS1 cells, and it was required for the associated induction of Ccnd1 and Mafa.The role of the transcription factor ETV5 in insulin exocytosis.Signal integration at the level of ion channel and exocytotic function in pancreatic β-cells.Novel roles of SUMO in pancreatic β-cells: thinking outside the nucleus.Protein sumoylation in brain development, neuronal morphology and spinogenesis.Adenylosuccinate Is an Insulin Secretagogue Derived from Glucose-Induced Purine Metabolism.The Roles of SUMO in Metabolic Regulation.The voltage-dependent potassium channel subunit Kv2.1 regulates insulin secretion from rodent and human islets independently of its electrical function.SUMOylation and calcium control syntaxin-1A and secretagogin sequestration by tomosyn to regulate insulin exocytosis in human ß cells.SUMOylation of Syntaxin1A regulates presynaptic endocytosisCross Talk between Adipose Tissue and Placenta in Obese and Gestational Diabetes Mellitus Pregnancies via Exosomes.Metabolomics applied to islet nutrient sensing mechanisms.How do reducing equivalents increase insulin secretion?Activity-dependent regulation of the sumoylation machinery in rat hippocampal neurons.Both conditional ablation and overexpression of E2 SUMO-conjugating enzyme (UBC9) in mouse pancreatic beta cells result in impaired beta cell function.Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men.Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion.A post-translational balancing act: the good and the bad of SUMOylation in pancreatic islets.Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx.
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P2860
SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
SUMOylation regulates insulin ...... docking in rodents and humans.
@en
type
label
SUMOylation regulates insulin ...... docking in rodents and humans.
@en
prefLabel
SUMOylation regulates insulin ...... docking in rodents and humans.
@en
P2093
P2860
P356
P1433
P1476
SUMOylation regulates insulin ...... docking in rodents and humans
@en
P2093
Catherine Hajmrle
Greg Plummer
Herbert Y Gaisano
Jocelyn E Manning Fox
Marina Casimir
Xiao-Qing Dai
Youhou Kang
P2860
P304
P356
10.2337/DB10-0440
P407
P577
2011-01-24T00:00:00Z