CD30 is a CD40-inducible molecule that negatively regulates CD40-mediated immunoglobulin class switching in non-antigen-selected human B cells.
about
The Epstein-Barr virus oncoprotein latent membrane protein 1 engages the tumor necrosis factor receptor-associated proteins TRADD and receptor-interacting protein (RIP) but does not induce apoptosis or require RIP for NF-kappaB activationRegulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombinationCD40 ligand in CLL pathogenesis and therapySelective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elementsPleiotropic signal transduction mediated by human CD30: a member of the tumor necrosis factor receptor (TNFR) familyDCs induce CD40-independent immunoglobulin class switching through BLyS and APRILSignaling by the germinal center kinase family of protein kinases.CD30 prevents T-cell responses to non-lymphoid tissues.Cowpox virus encodes a fifth member of the tumor necrosis factor receptor family: a soluble, secreted CD30 homologueViral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF.BAFF selectively enhances the survival of plasmablasts generated from human memory B cells.Immunoglobulin somatic hypermutation: double-strand DNA breaks, AID and error-prone DNA repair.Stromal endothelial cells establish a bidirectional crosstalk with chronic lymphocytic leukemia cells through the TNF-related factors BAFF, APRIL, and CD40L.Dysregulation of CD30+ T cells by leukemia impairs isotype switching in normal B cells.Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: definition of the requirements and modalities of hypermutation.EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cell-independent Ig heavy chain class switchingOngoing in vivo immunoglobulin class switch DNA recombination in chronic lymphocytic leukemia B cells.CD40 engagement triggers switching to IgA1 and IgA2 in human B cells through induction of endogenous TGF-beta: evidence for TGF-beta but not IL-10-dependent direct S mu-->S alpha and sequential S mu-->S gamma, S gamma-->S alpha DNA recombinationThe translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation.Deciphering CD30 ligand biology and its role in humoral immunity.Roles of TRAF molecules in B lymphocyte functionCD30 ligand/CD30 interaction is involved in pathogenesis of inflammatory bowel disease.Soluble CD30 binds to CD153 with high affinity and blocks transmembrane signaling by CD30.Engagement of CD153 (CD30 ligand) by CD30+ T cells inhibits class switch DNA recombination and antibody production in human IgD+ IgM+ B cells.AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation.Tetracyclines inhibit activated B cell function.
P2860
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P2860
CD30 is a CD40-inducible molecule that negatively regulates CD40-mediated immunoglobulin class switching in non-antigen-selected human B cells.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
CD30 is a CD40-inducible molec ...... ntigen-selected human B cells.
@en
type
label
CD30 is a CD40-inducible molec ...... ntigen-selected human B cells.
@en
prefLabel
CD30 is a CD40-inducible molec ...... ntigen-selected human B cells.
@en
P2093
P2860
P1433
P1476
CD30 is a CD40-inducible molec ...... antigen-selected human B cells
@en
P2093
P2860
P304
P356
10.1016/S1074-7613(00)80607-X
P407
P577
1998-08-01T00:00:00Z