5-Hydroxytryptamine is biotransformed by CYP2C9, 2C19 and 2B6 to hydroxylamine, which is converted into nitric oxide.

5-Hydroxytryptamine is biotransformed by CYP2C9, 2C19 and 2B6 to hydroxylamine, which is converted into nitric oxide.

Item
http://www.wikidata.org/entity/Q41869190
Phenobarbital increases monkey in vivo nicotine disposition and induces liver and brain CYP2B6 proteinGene variants in CYP2C19 are associated with altered in vivo bupropion pharmacokinetics but not bupropion-assisted smoking cessation outcomesMolecular characterization of CYP2B6 substratesCytochrome P450-mediated drug metabolism in the brainRedox control of asthma: molecular mechanisms and therapeutic opportunities.Genetic variability of drug-metabolizing enzymes: the dual impact on psychiatric therapy and regulation of brain function.Do we need pharmacogenetics to personalize antidepressant therapy?Brain drug-metabolizing cytochrome P450 enzymes are active in vivo, demonstrated by mechanism-based enzyme inhibition.Drug metabolism within the brain changes drug response: selective manipulation of brain CYP2B alters propofol effects.
P2860

5-Hydroxytryptamine is biotransformed by CYP2C9, 2C19 and 2B6 to hydroxylamine, which is converted into nitric oxide.

Item
http://www.wikidata.org/entity/Q41869190
description
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5-Hydroxytryptamine is biotran ...... s converted into nitric oxide.
@en
type
label
5-Hydroxytryptamine is biotran ...... s converted into nitric oxide.
@en
prefLabel
5-Hydroxytryptamine is biotran ...... s converted into nitric oxide.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
5-Hydroxytryptamine is biotran ...... s converted into nitric oxide.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932