Roles of the N- and C-terminal domains of carnitine palmitoyltransferase I isoforms in malonyl-CoA sensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved histidine residues.

Roles of the N- and C-terminal domains of carnitine palmitoyltransferase I isoforms in malonyl-CoA sensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved histidine residues.

Item
http://www.wikidata.org/entity/Q41920104
Structural model of a malonyl-CoA-binding site of carnitine octanoyltransferase and carnitine palmitoyltransferase I: mutational analysis of a malonyl-CoA affinity domainThe extreme C terminus of rat liver carnitine palmitoyltransferase I is not involved in malonyl-CoA sensitivity but in initial protein foldingEvidence of a malonyl-CoA-insensitive carnitine palmitoyltransferase I activity in red skeletal muscleIdentification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibitionPhosphorylation of rat liver mitochondrial carnitine palmitoyltransferase-I: effect on the kinetic properties of the enzymeAdenovirus-mediated overexpression of liver carnitine palmitoyltransferase I in INS1E cells: effects on cell metabolism and insulin secretionInhibition by etomoxir of rat liver carnitine octanoyltransferase is produced through the co-ordinate interaction with two histidine residuesPig liver carnitine palmitoyltransferase. Chimera studies show that both the N- and C-terminal regions of the enzyme are important for the unusual high malonyl-CoA sensitivityThe malonyl-CoA-long-chain acyl-CoA axis in the maintenance of mammalian cell function.C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesityGenetic polymorphisms in carnitine palmitoyltransferase 1A gene are associated with variation in body composition and fasting lipid traits in Yup'ik Eskimos.Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders.Structural insight into function and regulation of carnitine palmitoyltransferase.MLYCD mutation analysis: evidence for protein mistargeting as a cause of MLYCD deficiency.Sequencing and functional expression of the malonyl-CoA-sensitive carnitine palmitoyltransferase from Drosophila melanogaster.Cytological evidence that the C-terminus of carnitine palmitoyltransferase I is on the cytosolic face of the mitochondrial outer membrane.Reconstitution of purified, active and malonyl-CoA-sensitive rat liver carnitine palmitoyltransferase I: relationship between membrane environment and malonyl-CoA sensitivity.Genome duplication events have led to a diversification in the CPT I gene family in fish.Expression of FAS within hypothalamic neurons: a model for decreased food intake after C75 treatment.Mechanisms mediating insulin resistance in transgenic mice overexpressing mouse apolipoprotein A-II.A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme.
P2860
Q28564300-0729C7D0-3CDE-4DDE-ABE9-87092BDB60E1Q28577659-13A05F4F-577A-4460-8667-8C56F7A68FC9Q28578207-65CF24C7-2F30-4BB8-A721-C1B992954CACQ28579126-A27DEB31-16B9-4F31-992B-827365CDA3B4Q28579875-9A5FF661-A30F-4BFB-81E5-C296FDE92687Q28580422-EEAE71C2-666F-427F-A12A-9050DE3213D6Q28581761-C590D649-D5CD-4414-BE1F-275B14A4CE3DQ28582612-220E35A7-A323-4745-A557-E98566911F82Q33755073-42DE8724-D0D2-46E6-BB48-660DDE628103Q34035872-75705BE3-8D75-4A46-939B-E34521AD234DQ35625945-215432C8-F797-4DA7-A99B-EFE037869734Q37036681-5A6F18CB-DA77-4863-981C-4CE779D280E8Q37476799-CD3AA45B-927E-4857-B351-067386CAF6ABQ40637694-6638022C-511A-44F4-9A12-0A4B8C012779Q41809033-84FD6369-0B3A-48F1-BD18-9D0B3C922712Q42994236-3B71024D-7377-404D-9626-E4ABA40F4D53Q42996947-08FDCB72-39A3-4789-9B45-E2DE61C5395FQ44080062-D50E70A0-B424-4CEC-99D2-D49C1A0450EBQ44176882-5A562033-CE0B-4265-8C4F-6DCA89B90593Q45091537-6796F12D-9D1B-4FAB-94F9-ECFD577355F2Q46219022-0D967B11-D37A-4E52-8E23-CEBABCB5D960
P2860

Roles of the N- and C-terminal domains of carnitine palmitoyltransferase I isoforms in malonyl-CoA sensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved histidine residues.

Item
http://www.wikidata.org/entity/Q41920104
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Roles of the N- and C-terminal ...... conserved histidine residues.
@en
type
label
Roles of the N- and C-terminal ...... conserved histidine residues.
@en
prefLabel
Roles of the N- and C-terminal ...... conserved histidine residues.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P478
P577
P5875
P698
P932
P356
P1433
P1476
Roles of the N- and C-terminal ...... conserved histidine residues.
@en
P2093
P2860
P304
P31
P356
P407
P478
P577
P5875
P698
P932