Cytotoxic cholesterol is generated by the hydrolysis of cytoplasmic cholesteryl ester and transported to the plasma membrane.
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Decreased lipid efflux and increased susceptibility to cholesterol-induced apoptosis in macrophages lacking phosphatidylcholine transfer proteinMutations in yeast ARV1 alter intracellular sterol distribution and are complemented by human ARV1.ACAT inhibition reduces the progression of preexisting, advanced atherosclerotic mouse lesions without plaque or systemic toxicity.Membrane organization and regulation of cellular cholesterol homeostasis.Enantioselective protein-sterol interactions mediate regulation of both prokaryotic and eukaryotic inward rectifier K+ channels by cholesterol.Alzheimer disease beta-amyloid activity mimics cholesterol oxidase.Extracellular cholesterol-rich microdomains generated by human macrophages and their potential function in reverse cholesterol transport.Modulation of endothelial inward-rectifier K+ current by optical isomers of cholesterol.Metabolism, energetics, and lipid biology in the podocyte - cellular cholesterol-mediated glomerular injury.Molecular signal transduction in vascular cell apoptosis.Cholesterol sensitivity of KIR2.1 is controlled by a belt of residues around the cytosolic pore.Diabetes adversely affects macrophages during atherosclerotic plaque regression in mice.Cholesterol induces pancreatic β cell apoptosis through oxidative stress pathwayOxidation of LDL, atherogenesis, and apoptosis.Specific Kv1.3 blockade modulates key cholesterol-metabolism-associated molecules in human macrophages exposed to ox-LDL.Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's diseaseAcyl-coenzyme A:cholesterol acyltransferase promotes oxidized LDL/oxysterol-induced apoptosis in macrophagesCholesterol and Kir channels.Oxysterols in biological systems: the gastrointestinal tract, liver, vascular wall and central nervous system.ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity.An integrated approach for the mechanisms responsible for atherosclerotic plaque regressionNovel mechanism of U18666A-induced tumour necrosis factor-alpha production in RAW 264.7 macrophage cells.Comparative analysis of cholesterol sensitivity of Kir channels: role of the CD loop.Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress-induced death of motor neurons in amyotrophic lateral sclerosis.Mobilization of cytoplasmic CE droplets by overexpression of human macrophage cholesteryl ester hydrolase.Direct perturbation of lens membrane structure may contribute to cataracts caused by U18666A, an oxidosqualene cyclase inhibitor.Apoptosis and plaque destabilization in atherosclerosis: the role of macrophage apoptosis induced by cholesterol.Molecular dynamics simulations on the interaction of the transmembrane NavAb channel with cholesterol and lipids in the membrane.PET/CTA detection of muscle inflammation related to cholesterol crystal emboli without arterial obstruction.Increased hydrophilic plasma bile acids are correlated with protection from adiposity in skin-specific stearoyl-CoA desaturase-1 deficient miceA Discussion on the Relationship between Skin Lipid Metabolism and Whole-Body Glucose and Lipid Metabolism: Systematic Review
P2860
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P2860
Cytotoxic cholesterol is generated by the hydrolysis of cytoplasmic cholesteryl ester and transported to the plasma membrane.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Cytotoxic cholesterol is gener ...... ported to the plasma membrane.
@en
type
label
Cytotoxic cholesterol is gener ...... ported to the plasma membrane.
@en
prefLabel
Cytotoxic cholesterol is gener ...... ported to the plasma membrane.
@en
P2093
P1433
P1476
Cytotoxic cholesterol is gener ...... ported to the plasma membrane.
@en
P2093
Kellner-Weibel G
Rothblat GH
P304
P356
10.1016/S0021-9150(99)00155-0
P577
1999-10-01T00:00:00Z