Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel.
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Detrimental or beneficial: the role of TRPM2 in ischemia/reperfusion injuryAdenine Dinucleotide Second Messengers and T-lymphocyte Calcium SignalingTargeting TRPM2 in ROS-Coupled DiseasesInhibitory and excitatory neuromodulation by hydrogen peroxide: translating energetics to informationTPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomesOxidant Sensing by TRPM2 Inhibits Neutrophil Migration and Mitigates InflammationCharacterization of Danio rerio Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase, the structural prototype of the ADPRibase-Mn-like protein family.Putative chanzyme activity of TRPM2 cation channel is unrelated to pore gatingA splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α.Regulation of Substantia Nigra Pars Reticulata GABAergic Neuron Activity by H₂O₂ via Flufenamic Acid-Sensitive Channels and K(ATP) ChannelsThe key role of transient receptor potential melastatin-2 channels in amyloid-β-induced neurovascular dysfunction.Intracellular ATP supports TRPV6 activity via lipid kinases and the generation of PtdIns(4,5) P₂.H2O2: a dynamic neuromodulatorRole of TRP channels in the regulation of the endosomal pathway.Pore collapse underlies irreversible inactivation of TRPM2 cation channel currents.Cell death and autophagy under oxidative stress: roles of poly(ADP-Ribose) polymerases and Ca(2+).TRPM2 channels are required for NMDA-induced burst firing and contribute to H(2)O(2)-dependent modulation in substantia nigra pars reticulata GABAergic neuronsThe Sound of Silence: RNAi in Poly (ADP-Ribose) ResearchTRPM2: a multifunctional ion channel for calcium signalling.TRPM channels: same ballpark, different players, and different rules in immunogenetics.Molecular mechanisms of endolysosomal Ca2+ signalling in health and disease.The TRPM2 ion channel, an oxidative stress and metabolic sensor regulating innate immunity and inflammation.Oncogenic role and therapeutic target of transient receptor potential melastatin 7 channel in malignancy.Depletion of the Human Ion Channel TRPM2 in Neuroblastoma Demonstrates Its Key Role in Cell Survival through Modulation of Mitochondrial Reactive Oxygen Species and Bioenergetics.Functional characterisation of a TRPM2 orthologue from the sea anemone Nematostella vectensis in human cells.Redox regulation of transient receptor potential channels in the endothelium.Role of the phagosomal redox-sensitive TRP channel TRPM2 in regulating bactericidal activity of macrophages.The TRPM2 channel: A thermo-sensitive metabolic sensor.Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2'-phosphate.TRPM2 protects against tissue damage following oxidative stress and ischaemia-reperfusion.TRPM2 channels are not required for acute airway inflammation in OVA-induced severe allergic asthma in mice.Activators of TRPM2: Getting it right.Transient Receptor Potential-Melastatin Channel Family Member 2: Friend or FoeExpression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the rat.Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists.Neutrophil TRPM2 channels are implicated in the exacerbation of myocardial ischaemia/reperfusion injury.Different Principles of ADP-Ribose-Mediated Activation and Opposite Roles of the NUDT9 Homology Domain in the TRPM2 Orthologs of Man and Sea Anemone.Alteration in Intracellular Zn2+ Homeostasis as a Result of TRPM2 Channel Activation Contributes to ROS-Induced Hippocampal Neuronal Death.Multiple molecular mechanisms form a positive feedback loop driving amyloid β42 peptide-induced neurotoxicity via activation of the TRPM2 channel in hippocampal neurons.TRPM2: a candidate therapeutic target for treating neurological diseases.
P2860
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P2860
Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Identification of direct and i ...... atin 2 (TRPM2) cation channel.
@en
type
label
Identification of direct and i ...... atin 2 (TRPM2) cation channel.
@en
prefLabel
Identification of direct and i ...... atin 2 (TRPM2) cation channel.
@en
P2860
P356
P1476
Identification of direct and i ...... tatin 2 (TRPM2) cation channel
@en
P2093
Balázs Tóth
P2860
P304
30091-30102
P356
10.1074/JBC.M109.066464
P407
P577
2010-07-22T00:00:00Z