Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites.
about
Alpha-glucosidase promotes hemozoin formation in a blood-sucking bug: an evolutionary historyHDP-a novel heme detoxification protein from the malaria parasiteInterference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanolsArtemisinin, an Endoperoxide Antimalarial, Disrupts the Hemoglobin Catabolism and Heme Detoxification Systems in Malarial ParasiteOn the molecular mechanism of chloroquine's antimalarial actionHemozoin: oil versus water8-Aminoquinolines active against blood stage Plasmodium falciparum in vitro inhibit hematin polymerizationHemozoin and antimalarial drug discoveryThe heme biosynthesis pathway is essential for Plasmodium falciparum development in mosquito stage but not in blood stagesGlutathione transport: a new role for PfCRT in chloroquine resistanceMAHRP-1, a novel Plasmodium falciparum histidine-rich protein, binds ferriprotoporphyrin IX and localizes to the Maurer's cleftsMalarial hemozoin: from target to toolCharacterization of the chloroquine resistance transporter homologue in Toxoplasma gondiiHematin polymerization assay as a high-throughput screen for identification of new antimalarial pharmacophores.Identification and characterization of heme-interacting proteins in the malaria parasite, Plasmodium falciparum.A clinical drug library screen identifies astemizole as an antimalarial agent.Resonance Raman spectroscopy in malaria research.Beneficial effect of aurothiomalate on murine malaria.Crystallization of synthetic haemozoin (beta-haematin) nucleated at the surface of lipid particles.In vitro activities of benflumetol against 158 Senegalese isolates of Plasmodium falciparum in comparison with those of standard antimalarial drugs.Lipophilic mediated assays for beta-hematin inhibitors.Macrophage migration inhibitory factor release by macrophages after ingestion of Plasmodium chabaudi-infected erythrocytes: possible role in the pathogenesis of malarial anemiaOrder and specificity of the Plasmodium falciparum hemoglobin degradation pathwayThe hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex.Ligands of the peripheral benzodiazepine receptor are potent inhibitors of Plasmodium falciparum and Toxoplasma gondii in vitroPfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX.1,2-disubstituted ferrocenyl carbohydrate chloroquine conjugates as potential antimalarial agents.Membrane transport in the malaria-infected erythrocyte.Severe malarial anemia: innate immunity and pathogenesis.Molecular characterization and inhibition of a Plasmodium falciparum aspartic hemoglobinase.Heme and blood-feeding parasites: friends or foes?Probing the chloroquine resistance locus of Plasmodium falciparum with a novel class of multidentate metal(III) coordination complexes.Zinc protoporphyrin IX binds heme crystals to inhibit the process of crystallization in Plasmodium falciparumPlasmodium drug targets outside the genetic control of the parasite.Chloroquine resistance in the malarial parasite, Plasmodium falciparum.Emerging targets for antimalarial drugs.Potent antihematozoan activity of novel bisthiazolium drug T16: evidence for inhibition of phosphatidylcholine metabolism in erythrocytes infected with Babesia and Plasmodium spp.Synchrony in malaria infections: how intensifying within-host competition can be adaptiveImpact of malaria on genetic polymorphism and genetic diseases in Africans and African Americans.4-aminoquinoline analogs of chloroquine with shortened side chains retain activity against chloroquine-resistant Plasmodium falciparum
P2860
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P2860
Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Inhibition by chloroquine of a ...... ivity in malaria trophozoites.
@en
type
label
Inhibition by chloroquine of a ...... ivity in malaria trophozoites.
@en
prefLabel
Inhibition by chloroquine of a ...... ivity in malaria trophozoites.
@en
P356
P1433
P1476
Inhibition by chloroquine of a ...... ivity in malaria trophozoites.
@en
P2093
P2888
P304
P356
10.1038/355167A0
P407
P577
1992-01-01T00:00:00Z
P6179
1008555572