Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion.
about
Identification of a mammalian glycerol-3-phosphate phosphatase: Role in metabolism and signaling in pancreatic β-cells and hepatocytesLiver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling.Glucolipotoxicity of the pancreatic beta cell.Lipid oversupply, selective insulin resistance, and lipotoxicity: molecular mechanismsImplications of central obesity-related variants in LYPLAL1, NRXN3, MSRA, and TFAP2B on quantitative metabolic traits in adult Danes.Beta-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass.Lipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores.Perilipin 5 regulates islet lipid metabolism and insulin secretion in a cAMP-dependent manner: implication of its role in the postprandial insulin secretion.Development of diabetes in lean Ncb5or-null mice is associated with manifestations of endoplasmic reticulum and oxidative stress in beta cells.Analysis of two major intracellular phospholipases A(2) (PLA(2)) in mast cells reveals crucial contribution of cytosolic PLA(2)α, not Ca(2+)-independent PLA(2)β, to lipid mobilization in proximal mast cells and distal fibroblasts.FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling.Pancreatic β-Cell Dysfunction in Diet-Induced Obese Mice: Roles of AMP-Kinase, Protein Kinase Cε, Mitochondrial and Cholesterol Metabolism, and Alterations in Gene ExpressionCalcium-independent phospholipases A2 and their roles in biological processes and diseases.Differential Insulin Secretion of High-Fat Diet-Fed C57BL/6NN and C57BL/6NJ Mice: Implications of Mixed Genetic Background in Metabolic Studies.PGC-1 coactivators in β-cells regulate lipid metabolism and are essential for insulin secretion coupled to fatty acidsDistinct roles for alpha-beta hydrolase domain 5 (ABHD5/CGI-58) and adipose triglyceride lipase (ATGL/PNPLA2) in lipid metabolism and signaling.Biochemistry and pathophysiology of intravascular and intracellular lipolysis.Functional cardiac lipolysis in mice critically depends on comparative gene identification-58.A comprehensive lipidomic screen of pancreatic β-cells using mass spectroscopy defines novel features of glucose-stimulated turnover of neutral lipids, sphingolipids and plasmalogensUrea impairs β cell glycolysis and insulin secretion in chronic kidney disease.Desnutrin/ATGL activates PPARδ to promote mitochondrial function for insulin secretion in islet β cellsAdipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling.Pleiotropic regulation of mitochondrial function by adipose triglyceride lipase-mediated lipolysis.Metabolic fate of glucose and candidate signaling and excess-fuel detoxification pathways in pancreatic β-cells.Lysosomal acid lipase and lipophagy are constitutive negative regulators of glucose-stimulated insulin secretion from pancreatic beta cells.Transcribing β-cell mitochondria in health and disease.α/β-Hydrolase domain-6 and saturated long chain monoacylglycerol regulate insulin secretion promoted by both fuel and non-fuel stimuli.Simplified assays of lipolysis enzymes for drug discovery and specificity assessment of known inhibitors.Evidence for fatty acids mediating CL 316,243-induced reductions in blood glucose in mice.Lysophosphatidic acid impairs glucose homeostasis and inhibits insulin secretion in high-fat diet obese mice.Intracellular free fatty acid upholds β-cell glucose competence: The role of peroxisome proliferator-activated receptor δ and mitochondrial metabolism.A beta cell ATGL-lipolysis/adipose tissue axis controls energy homeostasis and body weight via insulin secretion in mice.Consequences of a fat diet in the distribution of minerals within pancreatic tissues of rats and rabbits.Phosphorylation of adipose triglyceride lipase Ser(404) is not related to 5'-AMPK activation during moderate-intensity exercise in humans.
P2860
Q28114936-5FD8B0E3-B29E-48DC-9041-492DD4AB9BD4Q30433187-8731FEE6-CAB7-4135-80B4-C8EEBD535801Q33665283-F6CC1C5E-FE1C-4C3C-A6D7-7925DDA0D50DQ33843550-41FFB84D-A0E9-4507-8466-E50E6795B2EAQ33933066-8A58E910-6E17-46A7-9A63-8CCA592A6179Q34082827-02C82EB3-DA5C-4948-808E-CE9DBF39D3C8Q34543395-AABB92D6-8D45-45E9-A2C2-7021E6C35FE2Q35220582-4FB84FE3-F88E-41B2-A893-CF61978DB6D0Q35256609-269A6BA0-D782-43F7-A5D1-B84954A0336AQ35423551-E097A619-245A-47ED-A583-3B789F0F5EFCQ35859576-35EC2758-0A63-4C81-8D98-A56F7AC1D9DAQ35979184-F84421D9-EC40-4AE9-980E-740BAB0DF00FQ35994344-B228FFA0-1652-4D6E-9333-52513C0EA4DEQ36073746-1FD6357E-0C0B-44EA-8440-7642BF1EC044Q36246011-EF8E92E2-B9EC-40A7-9CBC-D6C846979EFEQ36382868-1C348A60-274F-4D7A-AAD6-6D45F4ADFACFQ36708030-57B499EB-0FD7-42F6-8D8E-091D75DF5E90Q36742260-A3385EB3-D9CC-484C-8353-E727BA434445Q36928728-6F936940-9078-4415-AB01-B108A386E8D5Q37217519-CD0CF166-E8AA-4994-8A7C-55342300754BQ37410528-C794F61E-FA80-4B38-8001-26D36496C37BQ37431700-3BF08B23-2F8E-418F-A0CB-B4814981F96CQ38119380-2B59241C-EF04-4C83-8AA9-998B436B4635Q38712872-A040482F-785C-476C-BBFE-154B23912323Q39073469-2BC38802-8FC2-494F-AA2F-9E5162430AD9Q41689696-32BECD0C-91EB-48F5-B1D4-4E30D53B8161Q41769019-2AED5CB6-2D05-42F1-9CDD-A9878A9ECE10Q41906728-D2B16F35-983A-4866-BA88-68191C1F9B00Q41955324-C2C7C206-6315-483F-9CC2-9E6FB63ADDF6Q42435905-C08887B1-42A8-4873-9B49-46F5F16F42A1Q43192604-26BFB3FE-1927-40DB-A147-4120859515F4Q46484836-8BED3A6B-991A-4159-960D-B45A92F4EF9CQ53107388-1A439882-5B31-4975-B8A4-37FAD882A70AQ54503212-EAA36872-2946-4E1B-B515-91E91A3D9B6A
P2860
Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Adipose triglyceride lipase is ...... -stimulated insulin secretion.
@en
type
label
Adipose triglyceride lipase is ...... -stimulated insulin secretion.
@en
prefLabel
Adipose triglyceride lipase is ...... -stimulated insulin secretion.
@en
P2093
P2860
P50
P356
P1476
Adipose triglyceride lipase is ...... -stimulated insulin secretion.
@en
P2093
Claudiane Guay
Julien Lamontagne
Marc Prentki
Marco Pineda
Marie-Line Peyot
Martin G Latour
Roxane Lussier
S R Murthy Madiraju
P2860
P304
16848-16859
P356
10.1074/JBC.M109.006650
P407
P577
2009-04-22T00:00:00Z