Virally delivered channelrhodopsin-2 safely and effectively restores visual function in multiple mouse models of blindness.
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Optogenetics for neurodegenerative diseases.Multiple Independent Oscillatory Networks in the Degenerating RetinaEmerging gene therapies for retinal degenerationsOptogenetic approaches to retinal prosthesisAAV-mediated gene therapy in mouse models of recessive retinal degenerationRestoring the ON Switch in Blind Retinas: Opto-mGluR6, a Next-Generation, Cell-Tailored Optogenetic ToolOptogenetic Vision Restoration Using Rhodopsin for Enhanced Sensitivity.Pulse trains to percepts: the challenge of creating a perceptually intelligible world with sight recovery technologiesBiophysical Properties of Optogenetic Tools and Their Application for Vision Restoration ApproachesTherapeutic potential of optogenetic neuromodulationReview: the history and role of naturally occurring mouse models with Pde6b mutationsDevelopment and utility of an internal threshold control (ITC) real-time PCR assay for exogenous DNA detectionRestoration of visual function by expression of a light-gated mammalian ion channel in retinal ganglion cells or ON-bipolar cellsRestoration of the majority of the visual spectrum by using modified Volvox channelrhodopsin-1.Maintaining ocular safety with light exposure, focusing on devices for optogenetic stimulation.rAAV-mediated subcellular targeting of optogenetic tools in retinal ganglion cells in vivoOptogenetics.Utilizing Zebrafish Visual Behaviors in Drug Screening for Retinal DegenerationOptogenetic therapy for retinitis pigmentosa.Intrinsic bursting of AII amacrine cells underlies oscillations in the rd1 mouse retinaEfficient transduction and optogenetic stimulation of retinal bipolar cells by a synthetic adeno-associated virus capsid and promoter.PCR-based detection of gene transfer vectors: application to gene doping surveillance.A profile of transcriptomic changes in the rd10 mouse model of retinitis pigmentosa.Vector platforms for gene therapy of inherited retinopathies.Assessment of tropism and effectiveness of new primate-derived hybrid recombinant AAV serotypes in the mouse and primate retinaTargeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV Restores ON and OFF visual responses in blind miceOptogenetics for retinal disordersLiGluR restores visual responses in rodent models of inherited blindness.Focal damage to macaque photoreceptors produces persistent visual loss.Optical control after transfection of channelrhodopsin-2 recombinant adenovirus in visual cortical cellsChR2 mutants at L132 and T159 with improved operational light sensitivity for vision restorationPrinciples of designing interpretable optogenetic behavior experiments.Fast-conducting mechanoreceptors contribute to withdrawal behavior in normal and nerve injured ratsRetinoid receptors trigger neuritogenesis in retinal degenerationsDiversity of Chlamydomonas channelrhodopsins.Broad-Band Activatable White-OpsinFrequency and amplitude modulation have different effects on the percepts elicited by retinal stimulation.Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degenerationMutations in RD3 are associated with an extremely rare and severe form of early onset retinal dystrophy.A method for electrophysiological characterization of hamster retinal ganglion cells using a high-density CMOS microelectrode array.
P2860
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P2860
Virally delivered channelrhodopsin-2 safely and effectively restores visual function in multiple mouse models of blindness.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Virally delivered channelrhodo ...... ple mouse models of blindness.
@en
type
label
Virally delivered channelrhodo ...... ple mouse models of blindness.
@en
prefLabel
Virally delivered channelrhodo ...... ple mouse models of blindness.
@en
P2093
P2860
P356
P1433
P1476
Virally delivered channelrhodo ...... ple mouse models of blindness.
@en
P2093
A Cyrus Arman
Alan Horsager
Alapakkam P Sampath
Benjamin C Matteo
Edward S Boyden
Gabriel M Gordon
Jennifer A Lockridge
Jianwen Liu
Kenneth P Greenberg
Kimberly A Silka
P2860
P304
P356
10.1038/MT.2011.69
P577
2011-04-19T00:00:00Z