Widespread impact of nonsense-mediated mRNA decay on the yeast intronome. - Wikidata - awgldk - TriplyDB

Widespread impact of nonsense-mediated mRNA decay on the yeast intronome.

Widespread impact of nonsense-mediated mRNA decay on the yeast intronome.

http://www.wikidata.org/entity/Q41999821

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Regulated pre-mRNA splicing: the ghostwriter of the eukaryotic genome A single SR-like protein, Npl3, promotes pre-mRNA splicing in budding yeast.A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300.Alternative Splicing in Next Generation Sequencing Data of Saccharomyces cerevisiae.Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila.Environmental stresses inhibit splicing in the aquatic fungus Blastocladiella emersonii Nonsense-mediated decay enables intron gain in Drosophila.High-resolution profiling of NMD targets in yeast reveals translational fidelity as a basis for substrate selection.Detection and analysis of alternative splicing in Yarrowia lipolytica reveal structural constraints facilitating nonsense-mediated decay of intron-retaining transcripts.Nucleosome deposition and DNA methylation may participate in the recognition of premature termination codon in nonsense-mediated mRNA decay.Population genomics of intron splicing in 38 Saccharomyces cerevisiae genome sequences Nuclear expression of a group II intron is consistent with spliceosomal intron ancestry.Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe Specific splicing defects in S. pombe carrying a degron allele of the Survival of Motor Neuron gene Cryptic transcription mediates repression of subtelomeric metal homeostasis genes.Arabidopsis thaliana XRN2 is required for primary cleavage in the pre-ribosomal RNA.Is there a classical nonsense-mediated decay pathway in trypanosomes?Nuclear retention of unspliced pre-mRNAs by mutant DHX16/hPRP2, a spliceosomal DEAH-box protein.Quantification of pre-mRNA escape rate and synergy in splicing.Proofreading and spellchecking: a two-tier strategy for pre-mRNA splicing quality control.Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation Nonsense-mediated mRNA decay controls the changes in yeast ribosomal protein pre-mRNAs levels upon osmotic stress Imaging of endogenous messenger RNA splice variants in living cells reveals nuclear retention of transcripts inaccessible to nonsense-mediated decay in Arabidopsis.Widespread use of non-productive alternative splice sites in Saccharomyces cerevisiae Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question.Accumulation of noncoding RNA due to an RNase P defect in Saccharomyces cerevisiae.Key features of the two-intron Saccharomyces cerevisiae gene SUS1 contribute to its alternative splicing.Quality control of transcription start site selection by nonsense-mediated-mRNA decay Widespread exon skipping triggers degradation by nuclear RNA surveillance in fission yeast Nonsense-mediated RNA decay--a switch and dial for regulating gene expression Quality control of MATa1 splicing and exon skipping by nuclear RNA degradation.Alternative splicing and nonsense-mediated decay modulate expression of important regulatory genes in Arabidopsis.Sequencing of lariat termini in S. cerevisiae reveals 5' splice sites, branch points, and novel splicing events RNA secondary structure mediates alternative 3'ss selection in Saccharomyces cerevisiae Sequential RNA degradation pathways provide a fail-safe mechanism to limit the accumulation of unspliced transcripts in Saccharomyces cerevisiae.Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns NMD Classifier: A reliable and systematic classification tool for nonsense-mediated decay events.Extensive degradation of RNA precursors by the exosome in wild-type cells.The Rtr1p CTD phosphatase autoregulates its mRNA through a degradation pathway involving the REX exonucleases.Competition between pre-mRNAs for the splicing machinery drives global regulation of splicing.

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P2860

Widespread impact of nonsense-mediated mRNA decay on the yeast intronome.

http://www.wikidata.org/entity/Q41999821

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Widespread impact of nonsense-mediated mRNA decay on the yeast intronome.

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Widespread impact of nonsense-mediated mRNA decay on the yeast intronome.

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Widespread impact of nonsense-mediated mRNA decay on the yeast intronome.

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J.MOLCEL.2008.07.005

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Widespread impact of nonsense-mediated mRNA decay on the yeast intronome.

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Chrissie Young Lee

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Guillaume F Chanfreau

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Isabelle Toesca

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Michael Janis

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Shakir Sayani

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P2860

An unappreciated role for RNA surveillance

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

Identification of a regulated pathway for nuclear pre-mRNA turnover.

Targeting of aberrant mRNAs to cytoplasmic processing bodies.

Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1.

The economics of ribosome biosynthesis in yeast

The nonsense-mediated decay RNA surveillance pathway

The enzymes and control of eukaryotic mRNA turnover

The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon

Nonsense-mediated mRNA decay in health and disease

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360-370

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10.1016/J.MOLCEL.2008.07.005

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