Solution structure of the C4 zinc finger domain of HDM2.
about
Identification of a second Nutlin-3 responsive interaction site in the N-terminal domain of MDM2 using hydrogen/deuterium exchange mass spectrometryCancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradationIn vitro selection of mutant HDM2 resistant to Nutlin inhibitionStructure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activationMolecular characterization of the Ran-binding zinc finger domain of Nup153Structure of Human J-type Co-chaperone HscB Reveals a Tetracysteine Metal-binding DomainThe zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5' splice site-like sequencesCrystallographic and Biochemical Analysis of the Ran-binding Zinc Finger DomainThe PR/SET domain in PRDM4 is preceded by a zinc knuckleThe general definition of the p97/valosin-containing protein (VCP)-interacting motif (VIM) delineates a new family of p97 cofactorsThe chaperone ClpX stimulates expression of Staphylococcus aureus protein A by Rot dependent and independent pathwaysAutoactivation of the MDM2 E3 ligase by intramolecular interaction.The central region of HDM2 provides a second binding site for p53.Signaling to p53: ribosomal proteins find their way.Hydrophilic residues are crucial for ribosomal protein L11 (RPL11) interaction with zinc finger domain of MDM2 and p53 protein activationSplicing up mdm2 for cancer proteome diversity.Mice deficient in poly(C)-binding protein 4 are susceptible to spontaneous tumors through increased expression of ZFP871 that targets p53 for degradation.Intrinsically unstructured domains of Arf and Hdm2 form bimolecular oligomeric structures in vitro and in vivo.DNA topoisomerases: harnessing and constraining energy to govern chromosome topology.MDMX contains an autoinhibitory sequence element.Inhibitors of MDM2 and MDMX: a structural perspective.The evolution of MDM2 family genes.Regulation of the E3 ubiquitin ligase activity of MDM2 by an N-terminal pseudo-substrate motif.Redox properties of Cys2His2 and Cys4 zinc fingers determined by electrospray ionization mass spectrometry.
P2860
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P2860
Solution structure of the C4 zinc finger domain of HDM2.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
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2005年论文
@zh-cn
name
Solution structure of the C4 zinc finger domain of HDM2.
@en
Solution structure of the C4 zinc finger domain of HDM2.
@nl
type
label
Solution structure of the C4 zinc finger domain of HDM2.
@en
Solution structure of the C4 zinc finger domain of HDM2.
@nl
prefLabel
Solution structure of the C4 zinc finger domain of HDM2.
@en
Solution structure of the C4 zinc finger domain of HDM2.
@nl
P2093
P2860
P356
P1433
P1476
Solution structure of the C4 zinc finger domain of HDM2.
@en
P2093
Antonina Andreeva
Grace W Yu
Mark Bycroft
Mark D Allen
P2860
P304
P356
10.1110/PS.051927306
P50
P577
2005-12-29T00:00:00Z