ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex. - Wikidata - awgldk - TriplyDB

ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex.

ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex.

http://www.wikidata.org/entity/Q42070356

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Phosphoregulation of the WAVE regulatory complex and signal integration Steering tumor progression through the transcriptional response to growth factors and stroma WASp family verprolin-homologous protein-2 (WAVE2) and Wiskott-Aldrich syndrome protein (WASp) engage in distinct downstream signaling interactions at the T cell antigen receptor site ERK reinforces actin polymerization to power persistent edge protrusion during motility.Reactive oxygen species regulate protrusion efficiency by controlling actin dynamics Membrane Tension Acts Through PLD2 and mTORC2 to Limit Actin Network Assembly During Neutrophil Migration Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility WISp39 binds phosphorylated Coronin 1B to regulate Arp2/3 localization and Cofilin-dependent motility.Real-time monitoring of cell protrusion dynamics by impedance responses.Relaxation oscillations and hierarchy of feedbacks in MAPK signaling GnRH Induces ERK-Dependent Bleb Formation in Gonadotrope Cells, Involving Recruitment of Members of a GnRH Receptor-Associated Signalosome to the Blebs.AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve The RNA-binding protein SFPQ orchestrates an RNA regulon to promote axon viability The exocyst complex in exocytosis and cell migration.Kinetic analysis of BCL11B multisite phosphorylation-dephosphorylation and coupled sumoylation in primary thymocytes by multiple reaction monitoring mass spectroscopy.CDK1-mediated phosphorylation of Abi1 attenuates Bcr-Abl-induced F-actin assembly and tyrosine phosphorylation of WAVE complex during mitosis.Quantitative analysis of gradient sensing: towards building predictive models of chemotaxis in cancer.Down-regulation of CMTM8 induces epithelial-to-mesenchymal transition-like changes via c-MET/extracellular signal-regulated kinase (ERK) signaling.Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice.ERK-ERF-EGR1, a novel switch underlying acquisition of a motile phenotype.Luteolin inhibits migration of human glioblastoma U-87 MG and T98G cells through downregulation of Cdc42 expression and PI3K/AKT activity ERK signaling promotes cell motility by inducing the localization of myosin 1E to lamellipodial tips DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility.A conformational change within the WAVE2 complex regulates its degradation following cellular activation Abi1, a critical molecule coordinating actin cytoskeleton reorganization with PI-3 kinase and growth signaling.Molecular targets in the discovery and development of novel antimetastatic agents: current progress and future prospects.Micro-nanopatterning as tool to study the role of physicochemical properties on cell-surface interactions.Molecular mechanisms of asymmetric division in oocytes.IAPs on the move: role of inhibitors of apoptosis proteins in cell migration.Steering cell migration: lamellipodium dynamics and the regulation of directional persistence.Kinesins in cell migration.Tumor promotion by γ and suppression by β non-muscle actin isoforms.Biochemical reconstitution of the WAVE regulatory complex.Chemoattractant concentration-dependent tuning of ERK signaling dynamics in migrating neutrophils.Superresolution imaging of the cytoplasmic phosphatase PTPN22 links integrin-mediated T cell adhesion with autoimmunity.Signalling Pathways Controlling Cellular Actin Organization.Hairless but no longer clueless: understanding glandular trichome development.(R,R')-4'-methoxy-1-naphthylfenoterol targets GPR55-mediated ligand internalization and impairs cancer cell motility Fibronectin promotes directional persistence in fibroblast migration through interactions with both its cell-binding and heparin-binding domains.Muscle cells challenged with saturated fatty acids mount an autonomous inflammatory response that activates macrophages.

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ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex.

http://www.wikidata.org/entity/Q42070356

description

2011 nî lūn-bûn

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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2011年學術文章

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2011年學術文章

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name

ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex.

@en

ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex.

@nl

type

label

ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex.

@en

ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex.

@nl

prefLabel

ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex.

@en

ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex.

@nl

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J.MOLCEL.2011.02.031

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P1476

ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex.

@en

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Bryan A Ballif

http://www.w3.org/2001/XMLSchema#string

E Emrah Er

http://www.w3.org/2001/XMLSchema#string

Hunter L Elliott

http://www.w3.org/2001/XMLSchema#string

John Blenis

http://www.w3.org/2001/XMLSchema#string

Michelle C Mendoza

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Wenjuan Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Structure and control of the actin regulatory WAVE complex

Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics

Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs

Regulation of cell motility by mitogen-activated protein kinase

RACK1 targets the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway to link integrin engagement with focal adhesion disassembly and cell motility

Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation

PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation

Non-muscle myosin II takes centre stage in cell adhesion and migration

Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis

Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes

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661-671

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10.1016/J.MOLCEL.2011.02.031

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6

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Gaudenz Danuser

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21419341

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3078620

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