Impaired nitric oxide production in coronary endothelial cells of the spontaneously diabetic BB rat is due to tetrahydrobiopterin deficiency.
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Exercise training enhanced myocardial endothelial nitric oxide synthase (eNOS) function in diabetic Goto-Kakizaki (GK) ratsA yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactionsDeficient BH4 production via de novo and salvage pathways regulates NO responses to cytokines in adult cardiac myocytesTetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpressionRenal endothelial dysfunction in diabetic nephropathyCrystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP.Glutamine metabolism to glucosamine is necessary for glutamine inhibition of endothelial nitric oxide synthesisStructural basis of biopterin-induced inhibition of GTP cyclohydrolase I by GFRP, its feedback regulatory proteinSynergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liverRegulation of obesity and insulin resistance by nitric oxideTetrahydrobiopterin activates brown adipose tissue and regulates systemic energy metabolism.Role of NAD(P)H oxidase in superoxide generation and endothelial dysfunction in Goto-Kakizaki (GK) rats as a model of nonobese NIDDM.Tetrahydrobiopterin in cardiovascular health and disease.Curcumin supplementation could improve diabetes-induced endothelial dysfunction associated with decreased vascular superoxide production and PKC inhibitionTetrahydrobiopterin, superoxide, and vascular dysfunction.Tetrahydrobiopterin (BH4), a cofactor for nNOS, restores gastric emptying and nNOS expression in female diabetic ratsTyrosine nitration of PA700 activates the 26S proteasome to induce endothelial dysfunction in mice with angiotensin II-induced hypertension.Targeting the Pentose Phosphate Pathway in Syndrome X-related Cardiovascular Complications.Erythropoietin prevents endothelial dysfunction in GTP-cyclohydrolase I-deficient hph1 miceCellular basis of endothelial dysfunction in small mesenteric arteries from spontaneously diabetic (db/db -/-) mice: role of decreased tetrahydrobiopterin bioavailabilityAntioxidants and CVD in diabetes: where do we stand now.Modeling of biopterin-dependent pathways of eNOS for nitric oxide and superoxide production.Antiobesogenic role of endothelial nitric oxide synthase.Differential effects of eNOS uncoupling on conduit and small arteries in GTP-cyclohydrolase I-deficient hph-1 mice.M2 Macrophage Polarization Mediates Anti-inflammatory Effects of Endothelial Nitric Oxide Signaling.Decreased arteriolar tetrahydrobiopterin is linked to superoxide generation from nitric oxide synthase in mice fed high salt.Uncoupling of eNOS causes superoxide anion production and impairs NO signaling in the cerebral microvessels of hph-1 mice.Red blood cell ATP/ADP & nitric oxide: The best vasodilators in diabetic patients.Effects of Diabetes on Salivary Gland Protein Expression of Tetrahydrobiopterin and Nitric Oxide Synthesis and Function.Endothelial nitric oxide (NO) and its pathophysiologic regulationIncreased superoxide and endothelial NO synthase uncoupling in blood vessels of Bmal1-knockout mice.Tetrahydrobiopterin has a glucose-lowering effect by suppressing hepatic gluconeogenesis in an endothelial nitric oxide synthase-dependent manner in diabetic mice.Tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells.Endothelium-specific GTP cyclohydrolase I overexpression accelerates refractory wound healing by suppressing oxidative stress in diabetes.A study of endothelial function and circulating asymmetric dimethylarginine levels in people with Type 1 diabetes without macrovascular disease or microalbuminuriaGCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial functionSuperoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH.The Contrary Impact Of Diabetes And Exercise On Endothelial Nitric Oxide Synthase FunctionRatio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS.Peroxynitrite-dependent zinc release and inactivation of guanosine 5'-triphosphate cyclohydrolase 1 instigate its ubiquitination in diabetes.
P2860
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P2860
Impaired nitric oxide production in coronary endothelial cells of the spontaneously diabetic BB rat is due to tetrahydrobiopterin deficiency.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Impaired nitric oxide producti ...... etrahydrobiopterin deficiency.
@en
Impaired nitric oxide producti ...... etrahydrobiopterin deficiency.
@nl
type
label
Impaired nitric oxide producti ...... etrahydrobiopterin deficiency.
@en
Impaired nitric oxide producti ...... etrahydrobiopterin deficiency.
@nl
prefLabel
Impaired nitric oxide producti ...... etrahydrobiopterin deficiency.
@en
Impaired nitric oxide producti ...... etrahydrobiopterin deficiency.
@nl
P2093
P2860
P1433
P1476
Impaired nitric oxide producti ...... etrahydrobiopterin deficiency.
@en
P2093
C J Meininger
K Hatakeyama
R Martinez-Zaguilan
R S Marinos
P2860
P304
P356
10.1042/0264-6021:3490353
P407
P577
2000-07-01T00:00:00Z