Substrate-induced conformational transition in human phenylalanine hydroxylase as studied by surface plasmon resonance analyses: the effect of terminal deletions, substrate analogues and phosphorylation.
about
Integrating surface plasmon resonance biosensor-based interaction kinetic analyses into the lead discovery and optimization process.Phenylalanine hydroxylase misfolding and pharmacological chaperones.Substituting Tyr138 in the active site loop of human phenylalanine hydroxylase affects catalysis and substrate activation.Regulation of phenylalanine hydroxylase: conformational changes upon phosphorylation detected by H/D exchange and mass spectrometry.Probing the role of crystallographically defined/predicted hinge-bending regions in the substrate-induced global conformational transition and catalytic activation of human phenylalanine hydroxylase by single-site mutagenesis.Immobilized enzymes: understanding enzyme - surface interactions at the molecular level.
P2860
Substrate-induced conformational transition in human phenylalanine hydroxylase as studied by surface plasmon resonance analyses: the effect of terminal deletions, substrate analogues and phosphorylation.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Substrate-induced conformation ...... analogues and phosphorylation.
@en
Substrate-induced conformation ...... analogues and phosphorylation.
@nl
type
label
Substrate-induced conformation ...... analogues and phosphorylation.
@en
Substrate-induced conformation ...... analogues and phosphorylation.
@nl
prefLabel
Substrate-induced conformation ...... analogues and phosphorylation.
@en
Substrate-induced conformation ...... analogues and phosphorylation.
@nl
P2860
P356
P1433
P1476
Substrate-induced conformation ...... analogues and phosphorylation.
@en
P2093
Anne J Stokka
Torgeir Flatmark
P2860
P304
P356
10.1042/BJ20021009
P407
P577
2003-02-01T00:00:00Z