The structural basis of serpin polymerization studied by hydrogen/deuterium exchange and mass spectrometry.
about
AFM Imaging Reveals Topographic Diversity of Wild Type and Z Variant Polymers of Human α1-Proteinase InhibitorDefining the mechanism of polymerization in the serpinopathies.The tempered polymerization of human neuroserpin.Frustration in biomoleculesTherapeutic targeting of misfolding and conformational change in α1-antitrypsin deficiency.The Z mutation alters the global structural dynamics of α1-antitrypsin.PiZ mouse liver accumulates polyubiquitin conjugates that associate with catalytically active 26S proteasomesFolding mechanism of the metastable serpin α1-antitrypsin.Deficiency Mutations of Alpha-1 Antitrypsin. Effects on Folding, Function, and Polymerization.Structural insights into fibrinogen dynamics using amide hydrogen/deuterium exchange mass spectrometryAn antibody that prevents serpin polymerisation acts by inducing a novel allosteric behaviour.α(1)-antitrypsin deficiency and inflammation.Probing serpin conformational change using mass spectrometry and related methods.An antibody raised against a pathogenic serpin variant induces mutant-like behaviour in the wild-type protein.The pathological Trento variant of alpha-1-antitrypsin (E75V) shows nonclassical behaviour during polymerization.Functional unfolding of alpha1-antitrypsin probed by hydrogen-deuterium exchange coupled with mass spectrometry.Probing neuroserpin polymerization and interaction with amyloid-beta peptides using single molecule fluorescence.Probing the folding pathway of a consensus serpin using single tryptophan mutants.Electrophoresis- and FRET-Based Measures of Serpin Polymerization.On the molecular structure of human neuroserpin polymers.
P2860
Q28550962-D73F1F63-38BC-4955-AE9F-F70E484CDA91Q34182669-A90229BE-B1C6-4819-86DF-ACD4F7A16369Q34193142-9524D16C-30EF-4386-A151-F54979920730Q34635987-58E57E0B-415F-4F8F-B234-3B43371E63E4Q35214289-6AF80276-A23E-4525-AA8C-833DE8076B6AQ35236899-2B48A6CA-E37D-413E-A325-ABB9F34C93BEQ35247414-82358651-04D9-4E88-8952-08171F8F7275Q35849564-D8A8E256-C5BA-4BC6-9F66-78851CCD0711Q36549080-ABA1DB3A-D1B3-4E31-85C5-1BC167C946FCQ37291698-6A4F814E-5EC9-481B-9C77-311C36D2DA64Q37605015-8223D7FC-E6F0-4AD7-AEE1-D82D27D2C1A0Q37855954-3E476F8B-73ED-4B7E-B8EE-E3C31D4F7368Q37955396-907E40FC-3C28-4749-A1B9-EB65275BDFBDQ40356915-5105D900-FA99-4498-BB12-BE4EB54412F4Q41066319-0BFCFBB9-C0D6-4E27-AC21-F6166C67C68DQ42152439-E24E10F0-2DC5-426A-9191-EA80A4690D8DQ42183367-C9560099-F446-42A7-BD69-00A3F41DD878Q47640033-51021CF2-823C-4226-998E-AB34897453DFQ47818629-AF4CAC8E-8AFE-40A0-9C80-67EB23AA85ECQ50522986-753C22AB-5B70-4C86-B02D-4538DCF72584
P2860
The structural basis of serpin polymerization studied by hydrogen/deuterium exchange and mass spectrometry.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The structural basis of serpin ...... xchange and mass spectrometry.
@en
The structural basis of serpin ...... xchange and mass spectrometry.
@nl
type
label
The structural basis of serpin ...... xchange and mass spectrometry.
@en
The structural basis of serpin ...... xchange and mass spectrometry.
@nl
prefLabel
The structural basis of serpin ...... xchange and mass spectrometry.
@en
The structural basis of serpin ...... xchange and mass spectrometry.
@nl
P2093
P2860
P356
P1476
The structural basis of serpin ...... xchange and mass spectrometry.
@en
P2093
Barbara Kuri
Patrick L Wintrode
Tanusree Sengupta
Yuko Tsutsui
P2860
P304
30804-30811
P356
10.1074/JBC.M804048200
P407
P577
2008-09-15T00:00:00Z