Effects of acutely inhibiting PI3K isoforms and mTOR on regulation of glucose metabolism in vivo
about
Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetesModeling integrated cellular machinery using hybrid Petri-Boolean networksRole of phosphoinositide 3-OH kinase p110β in skeletal myogenesisSupramolecular nanoparticles that target phosphoinositide-3-kinase overcome insulin resistance and exert pronounced antitumor efficacy.Plasma Metabolomic Changes following PI3K Inhibition as Pharmacodynamic Biomarkers: Preclinical Discovery to Phase I Trial Evaluation.Structure, function and inhibition of the phosphoinositide 3-kinase p110α enzyme.BYL719, a new α-specific PI3K inhibitor: single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma.Targeting Metabolic Reprogramming by Influenza Infection for Therapeutic Intervention.Pharmacological inhibition of p110δ subunit of PI3K confers protection against experimental leishmaniasis.Biological characterization of SN32976, a selective inhibitor of PI3K and mTOR with preferential activity to PI3Kα, in comparison to established pan PI3K inhibitors.Phosphatidylinositol 3-kinase/Akt signaling pathway activates the WNK-OSR1/SPAK-NCC phosphorylation cascade in hyperinsulinemic db/db mice.Extended treatment with selective phosphatidylinositol 3-kinase and mTOR inhibitors has effects on metabolism, growth, behaviour and bone strength.PI3K p110γ overexpression in idiopathic pulmonary fibrosis lung tissue and fibroblast cells: in vitro effects of its inhibition.Examining changes in [18 F]FDG and [18 F]FLT uptake in U87-MG glioma xenografts as early response biomarkers to treatment with the dual mTOR1/2 inhibitor AZD8055.PI3Kα is essential for the recovery from Cre/tamoxifen cardiotoxicity and in myocardial insulin signalling but is not required for normal myocardial contractility in the adult heart.Global Expression Profiling and Pathway Analysis of Mouse Mammary Tumor Reveals Strain and Stage Specific Dysregulated Pathways in Breast Cancer Progression.
P2860
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P2860
Effects of acutely inhibiting PI3K isoforms and mTOR on regulation of glucose metabolism in vivo
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Effects of acutely inhibiting ...... of glucose metabolism in vivo
@en
Effects of acutely inhibiting ...... of glucose metabolism in vivo
@nl
type
label
Effects of acutely inhibiting ...... of glucose metabolism in vivo
@en
Effects of acutely inhibiting ...... of glucose metabolism in vivo
@nl
prefLabel
Effects of acutely inhibiting ...... of glucose metabolism in vivo
@en
Effects of acutely inhibiting ...... of glucose metabolism in vivo
@nl
P2093
P2860
P356
P1433
P1476
Effects of acutely inhibiting ...... of glucose metabolism in vivo
@en
P2093
Gordon W Rewcastle
Greg C Smith
Jackie D Kendall
Peter R Shepherd
Wee Kiat Ong
Weiping Han
P2860
P304
P356
10.1042/BJ20111913
P407
P577
2012-02-01T00:00:00Z