The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development. - Wikidata - awgldk - TriplyDB

The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.

The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.

http://www.wikidata.org/entity/Q42176868

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TGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease Activin receptor-like kinases: a diverse family playing an important role in cancer A New Subtype of Multiple Synostoses Syndrome Is Caused by a Mutation in GDF6 That Decreases Its Sensitivity to Noggin and Enhances Its Potency as a BMP Signal GDF-5 can act as a context-dependent BMP-2 antagonist.Common mutations in ALK2/ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders.Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects.Deletion of BMP receptor type IB decreased bone mass in association with compromised osteoblastic differentiation of bone marrow mesenchymal progenitors BMP signalling in skeletal development, disease and repair.Signaling pathways regulating cartilage growth plate formation and activity.TGF-β Family Signaling in Connective Tissue and Skeletal Diseases.The Effects of Class-Specific Histone Deacetylase Inhibitors on the Development of Limbs During Organogenesis.Palovarotene Inhibits Heterotopic Ossification and Maintains Limb Mobility and Growth in Mice With the Human ACVR1(R206H) Fibrodysplasia Ossificans Progressiva (FOP) Mutation BmpR1A is a major type 1 BMP receptor for BMP-Smad signaling during skull development.

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P2860

The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.

http://www.wikidata.org/entity/Q42176868

description

2015 nî lūn-bûn

@nan

2015年の論文

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2015年論文

@yue

2015年論文

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2015年論文

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2015年論文

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2015年論文

@zh-tw

2015年论文

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2015年论文

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name

The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.

@en

The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.

@nl

type

label

The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.

@en

The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.

@nl

prefLabel

The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.

@en

The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.

@nl

P1433

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P1433

Journal of Bone and Mineral Research

P1476

The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.

@en

P2093

Diana Rigueur

http://www.w3.org/2001/XMLSchema#string

Jong Kil Kim

http://www.w3.org/2001/XMLSchema#string

Karen M Lyons

http://www.w3.org/2001/XMLSchema#string

Sean Brugger

http://www.w3.org/2001/XMLSchema#string

Teni Anbarchian

http://www.w3.org/2001/XMLSchema#string

YooJin Lee

http://www.w3.org/2001/XMLSchema#string

P2860

A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo

ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development

ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation

Bone morphogenetic proteins

Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis

BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation

The ActR-I activin receptor protein is expressed in notochord, lens placode and pituitary primordium cells in the mouse embryo

Craniofacial defects in mice lacking BMP type I receptor Alk2 in neural crest cells

Developmental regulation of the growth plate

P304

733-741

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scholarly article

P356

10.1002/JBMR.2385

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4

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30

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2015-04-01T00:00:00Z

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25413979

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P932

4376569

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