Residues within the transmembrane domain of the glucagon-like peptide-1 receptor involved in ligand binding and receptor activation: modelling the ligand-bound receptor.
about
Structure of the human glucagon class B G-protein-coupled receptorA Hydrogen-Bonded Polar Network in the Core of the Glucagon-Like Peptide-1 Receptor Is a Fulcrum for Biased Agonism: Lessons from Class B Crystal StructuresGlucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic SuccessesGut-brain connection: The neuroprotective effects of the anti-diabetic drug liraglutideTransmembrane signal transduction by peptide hormones via family B G protein-coupled receptorsStructural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor (GLP-1R)Key interactions by conserved polar amino acids located at the transmembrane helical boundaries in Class B GPCRs modulate activation, effector specificity and biased signalling in the glucagon-like peptide-1 receptorAllosteric modulation of the activity of the glucagon-like peptide-1 (GLP-1) metabolite GLP-1 9-36 amide at the GLP-1 receptorGenetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R)Insights into the structure of class B GPCRs.Ligand binding pocket formed by evolutionarily conserved residues in the glucagon-like peptide-1 (GLP-1) receptor core domain.Second extracellular loop of human glucagon-like peptide-1 receptor (GLP-1R) differentially regulates orthosteric but not allosteric agonist binding and function.Structural Mapping and Functional Characterization of Zebrafish Class B G-Protein Coupled Receptor (GPCR) with Dual Ligand Selectivity towards GLP-1 and GlucagonPredicted structure of agonist-bound glucagon-like peptide 1 receptor, a class B G protein-coupled receptorRecent advances in understanding GLP-1R (glucagon-like peptide-1 receptor) function.Glucagon-like peptide-1: modulator of β-cell dysfunction and death.Paralog-divergent Features May Help Reduce Off-target Effects of Drugs: Hints from Glucagon Subfamily Analysis.Modulation of Glucagon Receptor Pharmacology by Receptor Activity-modifying Protein-2 (RAMP2).7TM Domain Structure of Adhesion GPCRs.The peptide agonist-binding site of the glucagon-like peptide-1 (GLP-1) receptor based on site-directed mutagenesis and knowledge-based modelling.Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein.The role of ECL2 in CGRP receptor activation: a combined modelling and experimental approach.Structural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor.Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies.Do plants contain g protein-coupled receptors?Crystal structure of the GLP-1 receptor bound to a peptide agonist.
P2860
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P2860
Residues within the transmembrane domain of the glucagon-like peptide-1 receptor involved in ligand binding and receptor activation: modelling the ligand-bound receptor.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Residues within the transmembr ...... ing the ligand-bound receptor.
@en
Residues within the transmembr ...... ing the ligand-bound receptor.
@nl
type
label
Residues within the transmembr ...... ing the ligand-bound receptor.
@en
Residues within the transmembr ...... ing the ligand-bound receptor.
@nl
prefLabel
Residues within the transmembr ...... ing the ligand-bound receptor.
@en
Residues within the transmembr ...... ing the ligand-bound receptor.
@nl
P2093
P2860
P356
P1476
Residues within the transmembr ...... ing the ligand-bound receptor.
@en
P2093
P2860
P304
P356
10.1210/ME.2011-1160
P577
2011-08-25T00:00:00Z