Targeted disruption of the S1P2 sphingosine 1-phosphate receptor gene leads to diffuse large B-cell lymphoma formation - Wikidata - awgldk - TriplyDB

Targeted disruption of the S1P2 sphingosine 1-phosphate receptor gene leads to diffuse large B-cell lymphoma formation

Targeted disruption of the S1P2 sphingosine 1-phosphate receptor gene leads to diffuse large B-cell lymphoma formation

http://www.wikidata.org/entity/Q42380774

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Sphingosine-1-Phosphate Receptor-2 Antagonists: Therapeutic Potential and Potential Risks Emerging role of sphingosine-1-phosphate signaling in head and neck squamous cell carcinoma S1PR2 links germinal center confinement and growth regulation Sphingosine-1 Phosphate: A New Modulator of Immune Plasticity in the Tumor Microenvironment Sphingolipid modulation of angiogenic factor expression in neuroblastoma.The sphingosine 1-phosphate receptor S1P₂ maintains the homeostasis of germinal center B cells and promotes niche confinement.Sphingosine-1-phosphate receptor 2 is critical for follicular helper T cell retention in germinal centers.Sphingosine 1-Phosphate Receptors: Do They Have a Therapeutic Potential in Cardiac Fibrosis?New developments in the pathology of malignant lymphoma: a review of the literature published from October 2009 to January 2010 An update on the biology of sphingosine 1-phosphate receptors.Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma An update on sphingosine-1-phosphate and other sphingolipid mediators.Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma.Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A.Sphingosine-1-phosphate receptor 2 Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy.Immunohistochemical analysis indicates that the anatomical location of B-cell non-Hodgkin's lymphoma is determined by differentially expressed chemokine receptors, sphingosine-1-phosphate receptors and integrins Sphingolipid signaling and hematopoietic malignancies: to the rheostat and beyond.Antitumor Activity of a Novel Sphingosine-1-Phosphate 2 Antagonist, AB1, in Neuroblastoma.Targeting sphingosine-1-phosphate in hematologic malignancies Stromal cell contribution to human follicular lymphoma pathogenesis.Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis.Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis Can Promote Mouse and Human Primary Mast Cell Angiogenic Potential through Upregulation of Vascular Endothelial Growth Factor-A and Matrix Metalloproteinase-2 Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells.Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing A sphingosine 1-phosphate receptor 2 selective allosteric agonist.Dissecting the role of the S1P/S1PR axis in health and disease.Targeting sphingosine-1-phosphate receptors in cancer.Sphingosine 1-phosphate signalling in cancer.Sphingosine-1-phosphate signaling in physiology and diseases.Oncogenic properties of sphingosine kinases in haematological malignancies.Role of Sphingolipids and Metabolizing Enzymes in Hematological Malignancies.Molecular mechanisms of target recognition by lipid GPCRs: relevance for cancer.Enhanced expression of transferrin receptor 1 contributes to oncogenic signalling by sphingosine kinase 1.Targeting sphingosine-1-phosphate signaling for cancer therapy."Dicing and Splicing" Sphingosine Kinase and Relevance to Cancer.Sphingosine 1-Phosphate Receptor 2 Regulates the Migration, Proliferation, and Differentiation of Mesenchymal Stem Cells.High frequency of development of B cell lymphoproliferation and diffuse large B cell lymphoma in Dbl knock-in mice.S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells.The role of G protein-coupled receptors in lymphoid malignancies.

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P2860

Targeted disruption of the S1P2 sphingosine 1-phosphate receptor gene leads to diffuse large B-cell lymphoma formation

http://www.wikidata.org/entity/Q42380774

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2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年论文

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name

Targeted disruption of the S1P ...... arge B-cell lymphoma formation

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Targeted disruption of the S1P ...... arge B-cell lymphoma formation

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Targeted disruption of the S1P ...... arge B-cell lymphoma formation

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Targeted disruption of the S1P ...... arge B-cell lymphoma formation

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Targeted disruption of the S1P ...... arge B-cell lymphoma formation

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Targeted disruption of the S1P ...... arge B-cell lymphoma formation

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Cancer Research

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Targeted disruption of the S1P ...... arge B-cell lymphoma formation

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A John MacLennan

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Alicia H Chaves

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Amy Chadburn

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Ashley M Mahler

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Jonathan Mandelbaum

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Nancy Lee

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Riccardo Dalla-Favera

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P2860

Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma.

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

Sphingosine 1-phosphate induces chemotaxis of immature and modulates cytokine-release in mature human dendritic cells for emergence of Th2 immune responses

The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

An essential role for the H218/AGR16/Edg-5/LP(B2) sphingosine 1-phosphate receptor in neuronal excitability

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

Biological roles of lysophospholipid receptors revealed by genetic null mice: an update.

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22

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69

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Laura Pasqualucci

Giorgio Cattoretti

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2009-11-10T00:00:00Z

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38080580

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19903857

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2973841

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