Mutations in PRP43 that uncouple RNA-dependent NTPase activity and pre-mRNA splicing function.
about
Biochemical characterization of the ATPase and helicase activity of UAP56, an essential pre-mRNA splicing and mRNA export factorSF1 and SF2 helicases: family mattersFunctional roles of DExD/H-box RNA helicases in Pre-mRNA splicingRegulation of DEAH/RHA helicases by G-patch proteinsRNA helicase proteins as chaperones and remodelersStructural basis for the function of DEAH helicasesRNA helicase module in an acetyltransferase that modifies a specific tRNA anticodonStructural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2Prp43p contains a processive helicase structural architecture with a specific regulatory domainA conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligationThe ATPase and helicase activities of Prp43p are stimulated by the G-patch protein Pfa1p during yeast ribosome biogenesis.Ntr1 activates the Prp43 helicase to trigger release of lariat-intron from the spliceosomeThe DEAD-box RNA helicase-like Utp25 is an SSU processome component.Insight into the roles of helicase motif Ia by characterizing Fanconi anemia group J protein (FANCJ) patient mutationsRoles of individual domains in the function of DHX29, an essential factor required for translation of structured mammalian mRNAsFunctional roles of protein splicing factors.Dynamic interactions of Ntr1-Ntr2 with Prp43 and with U5 govern the recruitment of Prp43 to mediate spliceosome disassemblyA conserved phenylalanine of motif IV in superfamily 2 helicases is required for cooperative, ATP-dependent binding of RNA substrates in DEAD-box proteinsA weak spliceosome-binding domain of Yju2 functions in the first step and bypasses Prp16 in the second step of splicingThe EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPaseATP-dependent unwinding of U4/U6 snRNAs by the Brr2 helicase requires the C terminus of Prp8.The mechanism of the second step of pre-mRNA splicing.Structural analyses of the pre-mRNA splicing machineryRegulation of Prp43-mediated disassembly of spliceosomes by its cofactors Ntr1 and Ntr2Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAUStructural and functional analysis of the RNA helicase Prp43 from the thermophilic eukaryote Chaetomium thermophilum.Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA.The target of the DEAH-box NTP triphosphatase Prp43 in Saccharomyces cerevisiae spliceosomes is the U2 snRNP-intron interaction.Insights into the activation of the helicase Prp43 by biochemical studies and structural mass spectrometry.Functional link between DEAH/RHA helicase Prp43 activation and ATP base binding.Structural insights into the mechanism of the DEAH-box RNA helicase Prp43De Novo Missense Mutations in DHX30 Impair Global Translation and Cause a Neurodevelopmental Disorder.Distinct RNA-unwinding mechanisms of DEAD-box and DEAH-box RNA helicase proteins in remodeling structured RNAs and RNPs.Identification of a 35S U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complex intermediate in spliceosome assembly.Structural Basis of DEAH/RHA Helicase ActivityThe DEAD-box protein Ded1 unwinds RNA duplexes by a mode distinct from translocating helicases
P2860
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P2860
Mutations in PRP43 that uncouple RNA-dependent NTPase activity and pre-mRNA splicing function.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Mutations in PRP43 that uncoup ...... nd pre-mRNA splicing function.
@en
Mutations in PRP43 that uncoup ...... nd pre-mRNA splicing function.
@nl
type
label
Mutations in PRP43 that uncoup ...... nd pre-mRNA splicing function.
@en
Mutations in PRP43 that uncoup ...... nd pre-mRNA splicing function.
@nl
prefLabel
Mutations in PRP43 that uncoup ...... nd pre-mRNA splicing function.
@en
Mutations in PRP43 that uncoup ...... nd pre-mRNA splicing function.
@nl
P2860
P356
P1433
P1476
Mutations in PRP43 that uncoup ...... nd pre-mRNA splicing function.
@en
P2093
Naoko Tanaka
P2860
P304
P356
10.1021/BI052656G
P407
P50
P577
2006-05-01T00:00:00Z