A novel link between the HER2-Akt and MDM2-p53 pathways via CSN6.

about

The COP9 signalosome subunit 6 (CSN6): a potential oncogene CDK inhibitor p57 (Kip2) is negatively regulated by COP9 signalosome subunit 6 CDK inhibitor p57 (Kip2) is downregulated by Akt during HER2-mediated tumorigenicity.

P2860

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P2860

A novel link between the HER2-Akt and MDM2-p53 pathways via CSN6.

Item

http://www.wikidata.org/entity/Q42414239

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

A novel link between the HER2-Akt and MDM2-p53 pathways via CSN6.

@en

A novel link between the HER2-Akt and MDM2-p53 pathways via CSN6.

@nl

type

Item

label

A novel link between the HER2-Akt and MDM2-p53 pathways via CSN6.

@en

A novel link between the HER2-Akt and MDM2-p53 pathways via CSN6.

@nl

prefLabel

A novel link between the HER2-Akt and MDM2-p53 pathways via CSN6.

@en

A novel link between the HER2-Akt and MDM2-p53 pathways via CSN6.

@nl

P1476

A novel link between the HER2-Akt and MDM2-p53 pathways via CSN6

@en

P2093

Tomoo Iwakuma

http://www.w3.org/2001/XMLSchema#string

P2860

Inhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapy

Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers.

HER2-Akt signaling in regulating COP9 signalsome subunit 6 and p53

Roles of COP9 signalosome in cancer.

Molecular biology in breast cancer: intrinsic subtypes and signaling pathways.

Mdm2 and MdmX partner to regulate p53.

Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation.

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation.

The COP9 signalosome

P304

4112

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P31

scholarly article

P356

10.4161/CC.22606

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Swathi V Iyer

P577

2012-10-25T00:00:00Z

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P5875

232705488

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P698

23099920

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P932

3524203

http://www.w3.org/2001/XMLSchema#string

A novel link between the HER2-Akt and MDM2-p53 pathways via CSN6.

about

P2860

P2860

A novel link between the HER2-Akt and MDM2-p53 pathways via CSN6.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932