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Mitochondria and mitophagy: the yin and yang of cell death controlThe Long Noncoding RNA MEG3 Contributes to Cisplatin Resistance of Human Lung AdenocarcinomaFunctional activation of mutant p53V172F by platinum analogs in cisplatin-resistant human tumor cells is dependent on serine-20 phosphorylationAberrant activation of p53 due to loss of MDM2 or MDMX causes early lens dysmorphogenesis.The traditional Chinese medical compound Rocaglamide protects nonmalignant primary cells from DNA damage-induced toxicity by inhibition of p53 expressionMDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer.Doxorubicin and 5-fluorouracil induced accumulation and transcriptional activity of p53 are independent of the phosphorylation at serine 15 in MCF-7 breast cancer cellsTargeting protein-protein interactions as an anticancer strategyThe MDM2 gene family.MID1 catalyzes the ubiquitination of protein phosphatase 2A and mutations within its Bbox1 domain disrupt polyubiquitination of alpha4 but not of PP2Ac.Association between MDM2 rs769412 and rs937283 polymorphisms with alcohol drinking and laryngeal carcinoma riskMolecular mechanisms of MYCN-dependent apoptosis and the MDM2-p53 pathway: an Achille's heel to be exploited for the therapy of MYCN-amplified neuroblastoma.Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cellsThe MDM2-p53 pathway revisitedEstrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer.The MID1 E3 ligase catalyzes the polyubiquitination of Alpha4 (α4), a regulatory subunit of protein phosphatase 2A (PP2A): novel insights into MID1-mediated regulation of PP2A.The E3 ubiquitin ligase XIAP restricts Anaplasma phagocytophilum colonization of Ixodes scapularis ticksHeterozygous p53(V172F) mutation in cisplatin-resistant human tumor cells promotes MDM4 recruitment and decreases stability and transactivity of p53.MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.Drug-dependent functionalization of wild-type and mutant p53 in cisplatin-resistant human ovarian tumor cellsOncoprotein stabilization in brain tumors.MDM2 285G>C and 344T>A gene variants and their association with hepatocellular carcinoma: a Moroccan case-control study.FL118 induces p53-dependent senescence in colorectal cancer cells by promoting degradation of MdmX.MDM2 gene polymorphisms and risk of classic Kaposi's sarcoma among Iranian patients.Deltex2 represses MyoD expression and inhibits myogenic differentiation by acting as a negative regulator of Jmjd1cMKRN2 is a novel ubiquitin E3 ligase for the p65 subunit of NF-κB and negatively regulates inflammatory responsesA novel link between the HER2-Akt and MDM2-p53 pathways via CSN6.OrfX, a Nucleomodulin Required for Listeria monocytogenes Virulence.Surface Plasmon Resonance Sensing of Biorecognition Interactions within the Tumor Suppressor p53 Network.The fate of murine double minute X (MdmX) is dictated by distinct signaling pathways through murine double minute 2 (Mdm2).The ubiquitin-proteasome pathway in adult and pediatric brain tumors: biological insights and therapeutic opportunities.Inhibition of Mdmx (Mdm4) in vivo induces anti-obesity effects.Crystal Structure of the C-terminal Domain of Human eIF2D and Its Implications on Eukaryotic Translation Initiation.Monitoring p53 by MDM2 and MDMX is required for endocrine pancreas development and function in a spatio-temporal manner.Potential therapeutic targets of TP53 gene in the context of its classically canonical functions and its latest non-canonical functions in human cancer.The role of p53 in myelodysplastic syndromes and acute myeloid leukemia: molecular aspects and clinical implications.Association of rs2279744 and rs117039649 promoter polymorphism with the risk of gynecological cancer: A meta-analysis of case-control studies.The p53/Adipose-Tissue/Cancer NexusNative PAGE to study the interaction between the oncosuppressor p53 and its protein ligands
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Mdm2 and MdmX partner to regulate p53.
@en
type
label
Mdm2 and MdmX partner to regulate p53.
@en
prefLabel
Mdm2 and MdmX partner to regulate p53.
@en
P2860
P1433
P1476
Mdm2 and MdmX partner to regulate p53.
@en
P2093
Xinjiang Wang
Xuejun Jiang
P2860
P304
P356
10.1016/J.FEBSLET.2012.02.049
P407
P577
2012-03-08T00:00:00Z