High-level transgene expression in nonhuman primate liver with novel adeno-associated virus serotypes containing self-complementary genomes.
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AAV-Delivered Antibody Mediates Significant Protective Effects against SIVmac239 Challenge in the Absence of Neutralizing ActivityRobust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution.In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses.Comparative study of anti-hepatitis B virus RNA interference by double-stranded adeno-associated virus serotypes 7, 8, and 9.Systematic evaluation of AAV vectors for liver directed gene transfer in murine models.Optimized adeno-associated virus (AAV)-protein phosphatase-5 helper viruses for efficient liver transduction by single-stranded AAV vectors: therapeutic expression of factor IX at reduced vector doses.Molecular analysis of vector genome structures after liver transduction by conventional and self-complementary adeno-associated viral serotype vectors in murine and nonhuman primate modelsRH10 provides superior transgene expression in mice when compared with natural AAV serotypes for neonatal gene therapy.Safe, long-term hepatic expression of anti-HCV shRNA in a nonhuman primate modelA simple method to increase the transduction efficiency of single-stranded adeno-associated virus vectors in vitro and in vivo.Adeno-associated virus serotype 9 vectors transduce murine alveolar and nasal epithelia and can be readministered.Recombinant AAV-directed gene therapy for type I glycogen storage diseases.AAV-mediated photoreceptor transduction of the pig cone-enriched retina.Percutaneous transendocardial delivery of self-complementary adeno-associated virus 6 achieves global cardiac gene transfer in canines.Recombinant adeno-associated virus-mediated inhibition of microRNA-21 protects mice against the lethal schistosome infection by repressing both IL-13 and transforming growth factor beta 1 pathways.The AAV vector toolkit: poised at the clinical crossroadsRecombinant AAV Vectors for Enhanced Expression of Authentic IgG.Recombinant adeno-associated virus vectors induce functionally impaired transgene product-specific CD8+ T cells in mice.Induction of rapid and highly efficient expression of the human ND4 complex I subunit in the mouse visual system by self-complementary adeno-associated virus.Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors.Myocardial gene delivery using molecular cardiac surgery with recombinant adeno-associated virus vectors in vivo.Multilineage transduction of resident lung cells in vivo by AAV2/8 for α1-antitrypsin gene therapy.Gene therapy for liver enzyme deficiencies: what have we learned from models for Crigler-Najjar and tyrosinemia?SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease.Adeno-associated virus-mediated gene transfer to nonhuman primate liver can elicit destructive transgene-specific T cell responses.Biodistribution and safety profile of recombinant adeno-associated virus serotype 6 vectors following intravenous delivery.Synergistic inhibition of PARP-1 and NF-κB signaling downregulates immune response against recombinant AAV2 vectors during hepatic gene therapy.Preexisting immunity and low expression in primates highlight translational challenges for liver-directed AAV8-mediated gene therapyNaturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints.Can Viruses be Modified to Achieve Sustained Gene Transfer.A new genetic vaccine platform based on an adeno-associated virus isolated from a rhesus macaque.Emerging Issues in AAV-Mediated In Vivo Gene Therapy.Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives.
P2860
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P2860
High-level transgene expression in nonhuman primate liver with novel adeno-associated virus serotypes containing self-complementary genomes.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
High-level transgene expressio ...... ng self-complementary genomes.
@en
High-level transgene expressio ...... ng self-complementary genomes.
@nl
type
label
High-level transgene expressio ...... ng self-complementary genomes.
@en
High-level transgene expressio ...... ng self-complementary genomes.
@nl
prefLabel
High-level transgene expressio ...... ng self-complementary genomes.
@en
High-level transgene expressio ...... ng self-complementary genomes.
@nl
P2093
P2860
P356
P1433
P1476
High-level transgene expressio ...... ng self-complementary genomes.
@en
P2093
Guang-Ping Gao
James M Wilson
Julie Johnston
Rebecca Grant
Roberto Calcedo
P2860
P304
P356
10.1128/JVI.00526-06
P407
P50
P577
2006-06-01T00:00:00Z