Xpd/Ercc2 regulates CAK activity and mitotic progression.
about
Stimulation of the XPB ATP-dependent helicase by the beta subunit of TFIIEDrosophila Xpd regulates Cdk7 localization, mitotic kinase activity, spindle dynamics, and chromosome segregationStructure of the DNA Repair Helicase XPDCDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction pointMicroRNA-27a regulates basal transcription by targeting the p44 subunit of general transcription factor IIH.The CDK-activating kinase (CAK) Csk1 is required for normal levels of homologous recombination and resistance to DNA damage in fission yeast.A unified model for the molecular basis of Xeroderma pigmentosum-Cockayne Syndrome.BEAF regulates cell-cycle genes through the controlled deposition of H3K9 methylation marks into its conserved dual-core binding sites.Human synthetic lethal inference as potential anti-cancer target gene detectionCyclin-dependent kinasesPremature aging and cancer in nucleotide excision repair-disorders.On the traces of XPD: cell cycle matters - untangling the genotype-phenotype relationship of XPD mutationsXPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase.Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.ERCC1 and ERCC2 polymorphisms and adult glioma.DNA repair and transcriptional deficiencies caused by mutations in the Drosophila p52 subunit of TFIIH generate developmental defects and chromosome fragility.DNA damage detection and repair, and the involvement of epigenetic states."Ready, set, go": checkpoint regulation by Cdk1 inhibitory phosphorylation.ARCH domain of XPD, an anchoring platform for CAK that conditions TFIIH DNA repair and transcription activitiesThe CDK Network: Linking Cycles of Cell Division and Gene Expression.Predictive value of ERCC1 and XPD polymorphism in patients with advanced non-small cell lung cancer receiving platinum-based chemotherapy: a systematic review and meta-analysis.Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair.Two steps forward, one step back: determining XPD helicase mechanism by single-molecule fluorescence and high-resolution optical tweezers.Fission yeast Cdk7 controls gene expression through both its CAK and C-terminal domain kinase activities.The role of XPD in cell apoptosis and viability and its relationship with p53 and cdk2 in hepatoma cells.Mechanisms involved in ceramide-induced cell cycle arrest in human hepatocarcinoma cells.Restoring DNA repair capacity of cells from three distinct diseases by XPD gene-recombinant adenovirus.Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics.Mat1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipocyte differentiation.A Drosophila XPD model links cell cycle coordination with neuro-development and suggests links to cancer.TFIIH controls developmentally-regulated cell cycle progression as a holocomplex.Arsenic-induced promoter hypomethylation and over-expression of ERCC2 reduces DNA repair capacity in humans by non-disjunction of the ERCC2-Cdk7 complex.Crumbs and Xpd in mitosis.Effects of selected genetic polymorphisms in xeroderma pigmentosum complementary group D on gastric cancer.Crumbs interacts with Xpd for nuclear division control in Drosophila.Mms19 is a mitotic gene that permits Cdk7 to be fully active as a Cdk-activating kinase.Iron Sulfur and Molybdenum Cofactor Enzymes Regulate the Drosophila Life Cycle by Controlling Cell Metabolism.XPD-The Lynchpin of NER: Molecule, Gene, Polymorphisms, and Role in Colorectal Carcinogenesis.Nucleotide excision repair gene subunit XPD is highly expressed in cervical squamous cell carcinoma.Xeroderma Pigmentosum Group D (XPD) Inhibits the Proliferation Cycle of Vascular Smooth Muscle Cell (VSMC) by Activating Glycogen Synthase Kinase 3β (GSK3β)
P2860
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P2860
Xpd/Ercc2 regulates CAK activity and mitotic progression.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Xpd/Ercc2 regulates CAK activity and mitotic progression.
@en
Xpd/Ercc2 regulates CAK activity and mitotic progression.
@nl
type
label
Xpd/Ercc2 regulates CAK activity and mitotic progression.
@en
Xpd/Ercc2 regulates CAK activity and mitotic progression.
@nl
prefLabel
Xpd/Ercc2 regulates CAK activity and mitotic progression.
@en
Xpd/Ercc2 regulates CAK activity and mitotic progression.
@nl
P2093
P356
P1433
P1476
Xpd/Ercc2 regulates CAK activity and mitotic progression.
@en
P2093
Beat Suter
Xiaoming Li
P2888
P304
P356
10.1038/NATURE01746
P407
P577
2003-07-01T00:00:00Z
P6179
1016877407