Ras activation in response to lysophosphatidic acid requires a permissive input from the epidermal growth factor receptor
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Differential requirement of the epidermal growth factor receptor for G protein-mediated activation of transcription factors by lysophosphatidic acid.Feedback activation of neurofibromin terminates growth factor-induced Ras activation.Transcriptional and post-transcriptional mechanisms for lysophosphatidic acid-induced cyclooxygenase-2 expression in ovarian cancer cells.Lysophosphatidic acid induces both EGFR-dependent and EGFR-independent effects on DNA synthesis and migration in pancreatic and colorectal carcinoma cells.Transactivation of PDGFRbeta by dopamine D4 receptor does not require PDGFRbeta dimerization.Optimal lysophosphatidic acid-induced DNA synthesis and cell migration but not survival require intact autophosphorylation sites of the epidermal growth factor receptor.RasGRP1 overexpression in T-ALL increases basal nucleotide exchange on Ras rendering the Ras/PI3K/Akt pathway responsive to protumorigenic cytokines.Ras activation in response to phorbol ester proceeds independently of the EGFR via an unconventional nucleotide-exchange factor system in COS-7 cells.Lysophosphatidic acid triggers calcium entry through a non-store-operated pathway in human neutrophils.
P2860
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P2860
Ras activation in response to lysophosphatidic acid requires a permissive input from the epidermal growth factor receptor
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name
Ras activation in response to ...... idermal growth factor receptor
@en
Ras activation in response to ...... idermal growth factor receptor
@nl
type
label
Ras activation in response to ...... idermal growth factor receptor
@en
Ras activation in response to ...... idermal growth factor receptor
@nl
prefLabel
Ras activation in response to ...... idermal growth factor receptor
@en
Ras activation in response to ...... idermal growth factor receptor
@nl
P2093
P2860
P356
P1433
P1476
Ras activation in response to ...... idermal growth factor receptor
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P2093
Ignacio Rubio
Knut Rennert
Reinhard Wetzker
Ute Wittig
P2860
P304
P356
10.1042/BJ20031410
P407
P577
2003-12-01T00:00:00Z