Gli1 is important for medulloblastoma formation in Ptc1+/- mice. - Wikidata - awgldk - TriplyDB

Gli1 is important for medulloblastoma formation in Ptc1+/- mice.

Gli1 is important for medulloblastoma formation in Ptc1+/- mice.

http://www.wikidata.org/entity/Q42476399

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Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway Hedgehog Signaling in Pancreatic Fibrosis and Cancer Targeting the Hedgehog Pathway in Pediatric Medulloblastoma Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis.Medulloblastoma: tumorigenesis, current clinical paradigm, and efforts to improve risk stratification Cerebellum development and medulloblastoma Development and cancer of the cerebellum Gli1 protein participates in Hedgehog-mediated specification of osteoblast lineage during endochondral ossification Signaling pathways in medulloblastoma.Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder Systems biology by the rules: hybrid intelligent systems for pathway modeling and discovery.Structure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription.Genetic variations regulate alternative splicing in the 5' untranslated regions of the mouse glioma-associated oncogene 1, Gli1.Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors.Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis.Amide conjugates of ketoprofen and indole as inhibitors of Gli1-mediated transcription in the Hedgehog pathway.Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis.Clinicopathological correlates of Gli1 expression in a population-based cohort of patients with newly diagnosed bladder cancer Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells.Hedgehog signaling restrains bladder cancer progression by eliciting stromal production of urothelial differentiation factors Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists.KIF7 Controls the Proliferation of Cells of the Respiratory Airway through Distinct Microtubule Dependent Mechanisms Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1 LncRNA BCAR4 wires up signaling transduction in breast cancer.Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice.Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma.Aggressive infantile embryonal tumors.GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein.Gli1 transcriptional activity is negatively regulated by AKT2 in neuroblastoma.A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway Hedgehog signaling regulates bladder cancer growth and tumorigenicity A sesquiterpene lactone from Siegesbeckia glabrescens suppresses Hedgehog/Gli-mediated transcription in pancreatic cancer cells.Hedgehog-Gli signaling pathway inhibitors as anticancer agents.In vitro models of pancreatic cancer for translational oncology research.SHH pathway and cerebellar development.Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.The Hedgehog's tale: developing strategies for targeting cancer.Matching mice to malignancy: molecular subgroups and models of medulloblastoma.Hedgehog pathway and GLI1 isoforms in human cancer.

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P2860

Gli1 is important for medulloblastoma formation in Ptc1+/- mice.

http://www.wikidata.org/entity/Q42476399

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2005 nî lūn-bûn

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name

Gli1 is important for medulloblastoma formation in Ptc1+/- mice.

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Gli1 is important for medulloblastoma formation in Ptc1+/- mice.

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type

label

Gli1 is important for medulloblastoma formation in Ptc1+/- mice.

@en

Gli1 is important for medulloblastoma formation in Ptc1+/- mice.

@nl

prefLabel

Gli1 is important for medulloblastoma formation in Ptc1+/- mice.

@en

Gli1 is important for medulloblastoma formation in Ptc1+/- mice.

@nl

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Gli1 is important for medulloblastoma formation in Ptc1+/- mice.

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Alexandra Joyner

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Daniel Stephen

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Hiromichi Kimura

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P2860

Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3

Physical and functional interactions between Zic and Gli proteins

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

Identification of PATCHED mutations in medulloblastomas by direct sequencing

Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1

Identification of genes expressed with temporal-spatial restriction to developing cerebellar neuron precursors by a functional genomic approach.

Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors

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medulloblastoma