Roscovitine, a selective CDK inhibitor, reduces the basal and estrogen-induced phosphorylation of ER-α in human ER-positive breast cancer cells.
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Roscovitine in cancer and other diseasesCR8, a selective and potent CDK inhibitor, provides neuroprotection in experimental traumatic brain injury.The impact of CDK inhibition in human malignancies associated with pronounced defects in apoptosis: advantages of multi-targeting small molecules.Palbociclib (PD 0332991) : targeting the cell cycle machinery in breast cancer.Selective CDK inhibitors: promising candidates for future clinical traumatic brain injury trials.CDK2-AP1 inhibits growth of breast cancer cells by regulating cell cycle and increasing docetaxel sensitivity in vivo and in vitroRoscovitine confers tumor suppressive effect on therapy-resistant breast tumor cellsTamoxifen non-estrogen receptor mediated molecular targets.Cyclin-dependent kinase 11(p110) (CDK11(p110)) is crucial for human breast cancer cell proliferation and growthThe impact of multi-targeted cyclin-dependent kinase inhibition in breast cancer cells: clinical implications.The cyclin-dependent kinase family in the social amoebozoan Dictyostelium discoideum.Why (multi)targeting of cyclin-dependent kinases is a promising therapeutic option for hormone-positive breast cancer and beyond.Interference with ER-α enhances the therapeutic efficacy of the selective CDK inhibitor roscovitine towards ER-positive breast cancer cells.Exploring the Relationship between the Inhibition Selectivity and the Apoptosis of Roscovitine-Treated Cancer Cells.MiR-873 regulates ERα transcriptional activity and tamoxifen resistance via targeting CDK3 in breast cancer cells.Inhibition of polyamine oxidase prevented cyclin-dependent kinase inhibitor-induced apoptosis in HCT 116 colon carcinoma cells.Targeting bromodomain and extraterminal proteins in breast cancer.Inhibition of E2F1 activity and cell cycle progression by arsenic via retinoblastoma protein.mTOR is a fine tuning molecule in CDK inhibitors-induced distinct cell death mechanisms via PI3K/AKT/mTOR signaling axis in prostate cancer cells.Conflicting evidence for the role of JNK as a target in breast cancer cell proliferation: Comparisons between pharmacological inhibition and selective shRNA knockdown approaches.The cyclin-dependent kinase inhibitor roscovitine inhibits kinase activity, cell proliferation, multicellular development, and Cdk5 nuclear translocation in Dictyostelium discoideum.
P2860
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P2860
Roscovitine, a selective CDK inhibitor, reduces the basal and estrogen-induced phosphorylation of ER-α in human ER-positive breast cancer cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Roscovitine, a selective CDK i ...... -positive breast cancer cells.
@en
Roscovitine, a selective CDK i ...... -positive breast cancer cells.
@nl
type
label
Roscovitine, a selective CDK i ...... -positive breast cancer cells.
@en
Roscovitine, a selective CDK i ...... -positive breast cancer cells.
@nl
prefLabel
Roscovitine, a selective CDK i ...... -positive breast cancer cells.
@en
Roscovitine, a selective CDK i ...... -positive breast cancer cells.
@nl
P2093
P2860
P356
P1476
Roscovitine, a selective CDK i ...... -positive breast cancer cells.
@en
P2093
David Gritsch
Józefa Węsierska-Gądek
Margarita Maurer
Nora Zulehner
Oxana Komina
P2860
P304
P356
10.1002/JCB.23004
P577
2011-03-01T00:00:00Z