High basal γH2AX levels sustain self-renewal of mouse embryonic and induced pluripotent stem cells. - Wikidata - awgldk - TriplyDB

High basal γH2AX levels sustain self-renewal of mouse embryonic and induced pluripotent stem cells.

High basal γH2AX levels sustain self-renewal of mouse embryonic and induced pluripotent stem cells.

http://www.wikidata.org/entity/Q42506988

about

Histone variants as emerging regulators of embryonic stem cell identity Reprogramming of cell fate: epigenetic memory and the erasure of memories past Phosphorylation and arginine methylation mark histone H2A prior to deposition during Xenopus laevis development.Genomic stability of lyophilized sheep somatic cells before and after nuclear transfer.A miR-590/Acvr2a/Rad51b axis regulates DNA damage repair during mESC proliferation Modification of topoisomerases in mammospheres derived from breast cancer cell line: clinical implications for combined treatments with tyrosine kinase inhibitors.Zscan4 is regulated by PI3-kinase and DNA-damaging agents and directly interacts with the transcriptional repressors LSD1 and CtBP2 in mouse embryonic stem cells Multiple facets of histone variant H2AX: a DNA double-strand-break marker with several biological functions.Persistent DNA damage-induced premature senescence alters the functional features of human bone marrow mesenchymal stem cells.Stella preserves maternal chromosome integrity by inhibiting 5hmC-induced γH2AX accumulation.High mobility group protein-mediated transcription requires DNA damage marker γ-H2AX.A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells.Sexually dimorphic expression of Dmrt1 and γH2AX in germ stem cells during gonadal development in Xenopus laevis.Dynamic culture improves cell reprogramming efficiency Response of Mouse Zygotes Treated with Mild Hydrogen Peroxide as a Model to Reveal Novel Mechanisms of Oxidative Stress-Induced Injury in Early Embryos.Analysis of alternative lengthening of telomere markers in BRCA1 defective cells.Myostatin induces DNA damage in skeletal muscle of streptozotocin-induced type 1 diabetic mice.Regulation of DNA Replication in Early Embryonic Cleavages.MicroRNA-3196 is inhibited by H2AX phosphorylation and attenuates lung cancer cell apoptosis by downregulating PUMA.Maintenance of genomic stability in mouse embryonic stem cells: relevance in aging and disease.MAD2L2 Promotes Open Chromatin in Embryonic Stem Cells and Derepresses the Dppa3 Locus Oocyte exposure to ZnO nanoparticles inhibits early embryonic development through the γ-H2AX and NF-κB signaling pathways.Alternative roles for oxidized mCs and TETs.Melatonin enhances the developmental competence of porcine somatic cell nuclear transfer embryos by preventing DNA damage induced by oxidative stress.Induced Pluripotent Stem Cells: Advances in the Quest for Genetic Stability during Reprogramming Process.Therapeutic doses of doxorubicin induce premature senescence of human mesenchymal stem cells derived from menstrual blood, bone marrow and adipose tissue.

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High basal γH2AX levels sustain self-renewal of mouse embryonic and induced pluripotent stem cells.

http://www.wikidata.org/entity/Q42506988

description

2012 nî lūn-bûn

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2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

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2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

High basal γH2AX levels sustai ...... nduced pluripotent stem cells.

@en

High basal γH2AX levels sustai ...... nduced pluripotent stem cells.

@nl

type

label

High basal γH2AX levels sustai ...... nduced pluripotent stem cells.

@en

High basal γH2AX levels sustai ...... nduced pluripotent stem cells.

@nl

prefLabel

High basal γH2AX levels sustai ...... nduced pluripotent stem cells.

@en

High basal γH2AX levels sustai ...... nduced pluripotent stem cells.

@nl

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High basal γH2AX levels sustai ...... nduced pluripotent stem cells.

@en

P2093

Alessandro Cignetti

http://www.w3.org/2001/XMLSchema#string

Benjamin Kumpfmueller

http://www.w3.org/2001/XMLSchema#string

Claudia Giachino

http://www.w3.org/2001/XMLSchema#string

Elisa Cibrario Rocchietti

http://www.w3.org/2001/XMLSchema#string

Lisa Accomasso

http://www.w3.org/2001/XMLSchema#string

Melanie J Welham

http://www.w3.org/2001/XMLSchema#string

Michael P Storm

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Paola Circosta

http://www.w3.org/2001/XMLSchema#string

Paola Porcedda

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Valentina Minieri

http://www.w3.org/2001/XMLSchema#string

P2860

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

Chromatin modifications and their function

Generation of germline-competent induced pluripotent stem cells

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

P304

1414-1423

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scholarly article

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10.1002/STEM.1133

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7

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30

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Silvia Saviozzi

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2012-07-01T00:00:00Z

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225044221

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22628289

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