Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress - Wikidata - awgldk - TriplyDB

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

http://www.wikidata.org/entity/Q28201846

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Nucleotide excision repair is associated with the replisome and its efficiency depends on a direct interaction between XPA and PCNA Interplay between human DNA repair proteins at a unique double-strand break in vivo Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity CtIP is required to initiate replication-dependent interstrand crosslink repair Metnase promotes restart and repair of stalled and collapsed replication forks Tumor suppressor protein C53 antagonizes checkpoint kinases to promote cyclin-dependent kinase 1 activation FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling Human UPF1 interacts with TPP1 and telomerase and sustains telomere leading-strand replication A role for DEAD box 1 at DNA double-strand breaks Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage Phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular response to DNA damage A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalization Preferential localization of hyperphosphorylated replication protein A to double-strand break repair and checkpoint complexes upon DNA damage Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo Epigenetic modifications in double-strand break DNA damage signaling and repair Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle Mre11 assembles linear DNA fragments into DNA damage signaling complexes Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapy Replication Stress: A Lifetime of Epigenetic Change Modulation of DNA damage and repair pathways by human tumour viruses A peek into the complex realm of histone phosphorylation TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenance Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis Periodic Exposure of Keratinocytes to Cold Physical Plasma: An In Vitro Model for Redox-Related Diseases of the Skin.Dephosphorylation of gamma H2A by Glc7/protein phosphatase 1 promotes recovery from inhibition of DNA replication.Saccharomyces cerevisiae histone H2A Ser122 facilitates DNA repair.Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling NFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-amino acid repeat sequence, is an early participant in DNA damage response NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways Recruitment of the cell cycle checkpoint kinase ATR to chromatin during S-phase Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis

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Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

http://www.wikidata.org/entity/Q28201846

description

2001 nî lūn-bûn

@nan

2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Histone H2AX is phosphorylated ...... sponse to replicational stress

@ast

Histone H2AX is phosphorylated ...... sponse to replicational stress

@en

Histone H2AX is phosphorylated ...... sponse to replicational stress

@nl

type

label

Histone H2AX is phosphorylated ...... sponse to replicational stress

@ast

Histone H2AX is phosphorylated ...... sponse to replicational stress

@en

Histone H2AX is phosphorylated ...... sponse to replicational stress

@nl

prefLabel

Histone H2AX is phosphorylated ...... sponse to replicational stress

@ast

Histone H2AX is phosphorylated ...... sponse to replicational stress

@en

Histone H2AX is phosphorylated ...... sponse to replicational stress

@nl

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Journal of Biological Chemistry

P1476

Histone H2AX is phosphorylated ...... sponse to replicational stress

@en

P2093

I M Ward

http://www.w3.org/2001/XMLSchema#string

J Chen

http://www.w3.org/2001/XMLSchema#string

P2860

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

Megabase chromatin domains involved in DNA double-strand breaks in vivo

A role for Saccharomyces cerevisiae histone H2A in DNA repair.

The DNA damage response: putting checkpoints in perspective

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX

Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

Physical interactions among human checkpoint control proteins HUS1p, RAD1p, and RAD9p, and implications for the regulation of cell cycle progression

Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

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47759-62

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scholarly article

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1050255

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10.1074/JBC.C100569200

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51

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276

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2001-12-21T00:00:00Z

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11673449

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P921

phosphorylation