Upregulation of type I collagen by TGF-beta in mesangial cells is blocked by PPARgamma activation. - Wikidata - awgldk - TriplyDB

Upregulation of type I collagen by TGF-beta in mesangial cells is blocked by PPARgamma activation.

Upregulation of type I collagen by TGF-beta in mesangial cells is blocked by PPARgamma activation.

http://www.wikidata.org/entity/Q42518271

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Telmisartan but not valsartan inhibits TGF-beta-mediated accumulation of extracellular matrix via activation of PPARgamma PPARgamma agonists inhibit TGF-beta-PKA signaling in glomerulosclerosis.A synthetic PPAR-γ agonist triterpenoid ameliorates experimental fibrosis: PPAR-γ-independent suppression of fibrotic responses PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target.Homocysteine and Hypertension in Diabetes: Does PPARgamma Have a Regulatory Role?Activation of PPARs α, β/δ, and γ Impairs TGF-β1-Induced Collagens' Production and Modulates the TIMP-1/MMPs Balance in Three-Dimensional Cultured Chondrocytes.Involvement of PPAR nuclear receptors in tissue injury and wound repair Glomerular aging in females is a multi-stage reversible process mediated by phenotypic changes in progenitors.The glomerulosclerosis of aging in females: contribution of the proinflammatory mesangial cell phenotype to macrophage infiltration.Constitutive Smad signaling and Smad-dependent collagen gene expression in mouse embryonic fibroblasts lacking peroxisome proliferator-activated receptor-gamma.Growth factors and the development of diabetic nephropathy.Thiazolidinediones and Risk of Long-Term Dialysis in Diabetic Patients with Advanced Chronic Kidney Disease: A Nationwide Cohort Study.hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists.Resistance to glomerulosclerosis in B6 mice disappears after menopause.Peroxisome proliferator-activated receptor γ: innate protection from excessive fibrogenesis and potential therapeutic target in systemic sclerosis Antidiabetic effects of Corni Fructus extract in streptozotocin-induced diabetic rats Regulation of Matrix Remodeling by Peroxisome Proliferator-Activated Receptor-γ: A Novel Link Between Metabolism and Fibrogenesis.The role of nuclear receptors in the kidney in obesity and metabolic syndrome Protective effect of peroxisome proliferator activated receptor gamma agonists on diabetic and non-diabetic renal diseases.PPAR-gamma agonists and diabetic nephropathy.Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) agonists attenuate the profibrotic response induced by TGF-beta1 in renal interstitial fibroblasts MicroRNA-27a Induces Mesangial Cell Injury by Targeting of PPARγ, and its In Vivo Knockdown Prevents Progression of Diabetic Nephropathy PPARs and the kidney in metabolic syndrome.Identifying advanced glycation end products as a major source of oxidants in aging: implications for the management and/or prevention of reduced renal function in elderly persons Peroxisome proliferator-activated receptor-gamma abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator.Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities.Fibrosis in systemic sclerosis: emerging concepts and implications for targeted therapy.The renoprotective actions of peroxisome proliferator-activated receptors agonists in diabetes.Molecular basis of organ fibrosis: potential therapeutic approaches.Complexity of diabetic nephropathy pathogenesis and design of investigations.The role of PPARγ-mediated signalling in skin biology and pathology: new targets and opportunities for clinical dermatology.Lipotoxicity as a trigger factor of renal disease.Peroxisome proliferator activating receptor-γ and the podocyte.Rhein reverses the diabetic phenotype of mesangial cells over-expressing the glucose transporter (GLUT1) by inhibiting the hexosamine pathway.Inhibitory effects of peroxisome proliferator-activated receptor γ agonists on collagen IV production in podocytes.Structurally Programmed Assembly of Translation Initiation Nanoplex for Superior mRNA Delivery.Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma.Omacor, n-3 polyunsaturated fatty acid, attenuated albuminuria and renal dysfunction with decrease of SREBP-1 expression and triglyceride amount in the kidney of type II diabetic animals.A biodegradable polyurethane-ascorbic acid scaffold for bone tissue engineering.

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P2860

Upregulation of type I collagen by TGF-beta in mesangial cells is blocked by PPARgamma activation.

http://www.wikidata.org/entity/Q42518271

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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2002年學術文章

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2002年學術文章

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name

Upregulation of type I collage ...... ocked by PPARgamma activation.

@en

Upregulation of type I collage ...... ocked by PPARgamma activation.

@nl

type

label

Upregulation of type I collage ...... ocked by PPARgamma activation.

@en

Upregulation of type I collage ...... ocked by PPARgamma activation.

@nl

prefLabel

Upregulation of type I collage ...... ocked by PPARgamma activation.

@en

Upregulation of type I collage ...... ocked by PPARgamma activation.

@nl

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AJPRENAL.00189.2001

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American Journal of Physiology - Renal Physiology

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Upregulation of type I collage ...... ocked by PPARgamma activation.

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P2093

Alessia Fornoni

http://www.w3.org/2001/XMLSchema#string

Feng Zheng

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Gary E Striker

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Liliane J Striker

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Matthew D Breyer

http://www.w3.org/2001/XMLSchema#string

Sharon J Elliot

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Youfei Guan

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P2860

TGF beta signals through a heteromeric protein kinase receptor complex

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

Expression and function of peroxisome proliferator-activated receptor-gamma in mesangial cells.

Peroxisome proliferator-activated receptors: insight into multiple cellular functions.

Roles of PPARs in health and disease.

Role of mesangial cells in glomerulosclerosis.

Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids

Suppression of collagenase gene expression by all-trans and 9-cis retinoic acid is ligand dependent and requires both RARs and RXRs.

Peroxisome proliferator-activated receptor gamma1 (PPARgamma1) expresses in rat mesangial cells and PPARgamma agonists modulate its differentiation.

Differential regulation of macrophage peroxisome proliferator-activated receptor expression by glucose : role of peroxisome proliferator-activated receptors in lipoprotein lipase gene expression.

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