The common rs9939609 gene variant of the fat mass- and obesity-associated gene FTO is related to fat cell lipolysis. - Wikidata - awgldk - TriplyDB

The common rs9939609 gene variant of the fat mass- and obesity-associated gene FTO is related to fat cell lipolysis.

The common rs9939609 gene variant of the fat mass- and obesity-associated gene FTO is related to fat cell lipolysis.

http://www.wikidata.org/entity/Q42521971

about

FTO: the first gene contributing to common forms of human obesity Role of FTO in Adipocyte Development and Function: Recent Insights Obesity-associated variants within FTO form long-range functional connections with IRX3 The obesity-associated polymorphisms FTO rs9939609 and MC4R rs17782313 and endometrial cancer risk in non-Hispanic white women Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS).FTO variant rs9939609 is associated with body mass index and waist circumference, but not with energy intake or physical activity in European- and African-American youth Association of genetic polymorphism of PPARγ-2, ACE, MTHFR, FABP-2 and FTO genes in risk prediction of type 2 diabetes mellitus Regulation of Fto/Ftm gene expression in mice and humans.Recent progress in the genetics of common obesity Interaction between FTO rs9939609 and the Native American-origin ABCA1 rs9282541 affects BMI in the admixed Mexican population Genetic variation at the FTO locus influences RBL2 gene expression.FTO genotype is associated with exercise training-induced changes in body composition.From monogenic to polygenic obesity: recent advances.Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development.Genetic association of FTO/IRX region with obesity and overweight in the Polish population.FTO gene polymorphisms and obesity risk: a meta-analysis.Impact of metabolic regulators on the expression of the obesity associated genes FTO and NAMPT in human preadipocytes and adipocytes The genetics of obesity: FTO leads the way.The effects of genetic variation in FTO rs9939609 on obesity and dietary preferences in Chinese Han children and adolescents.Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index Fat mass and obesity-associated (FTO) gene polymorphisms are associated with physical activity, food intake, eating behaviors, psychological health, and modeled change in body mass index in overweight/obese Caucasian adults Knockdown of the fat mass and obesity gene disrupts cellular energy balance in a cell-type specific manner.FTO is increased in muscle during type 2 diabetes, and its overexpression in myotubes alters insulin signaling, enhances lipogenesis and ROS production, and induces mitochondrial dysfunction.FTO influences adipogenesis by regulating mitotic clonal expansion Overexpression of Fto leads to increased food intake and results in obesity Common variant rs9939609 in gene FTO confers risk to polycystic ovary syndrome.Gene-diet interactions in childhood obesity.Genetics and epigenetics of obesity.Associations between FTO genotype and total energy and macronutrient intake in adults: a systematic review and meta-analysis.Association of FTO polymorphisms with early age of obesity in obese Italian subjects Interactions between the FTO rs9939609 polymorphism, body mass index, and lifestyle-related factors on metabolic syndrome risk.Recent advances in obesity: genetics and beyond.Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing.Physical activity and FTO genotype by physical activity interactive influences on obesity Novel SNP in the coding region of the FTO gene is associated with marbling score in Hanwoo (Korean cattle).Fat mass and obesity associated (FTO) gene influences skeletal muscle phenotypes in non-resistance trained males and elite rugby playing position Complete re-sequencing of a 2Mb topological domain encompassing the FTO/IRXB genes identifies a novel obesity-associated region upstream of IRX5.FTO modulates fibrogenic responses in obstructive nephropathy.Variations in the FTO gene are associated with severe obesity in the Japanese

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The common rs9939609 gene variant of the fat mass- and obesity-associated gene FTO is related to fat cell lipolysis.

http://www.wikidata.org/entity/Q42521971

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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name

The common rs9939609 gene vari ...... related to fat cell lipolysis.

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The common rs9939609 gene vari ...... related to fat cell lipolysis.

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type

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The common rs9939609 gene vari ...... related to fat cell lipolysis.

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The common rs9939609 gene vari ...... related to fat cell lipolysis.

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The common rs9939609 gene vari ...... related to fat cell lipolysis.

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The common rs9939609 gene vari ...... related to fat cell lipolysis.

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JLR.M700448-JLR200

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Journal of Lipid Research

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The common rs9939609 gene vari ...... related to fat cell lipolysis.

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Eva Sjölin

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Johan Hoffstedt

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Kerstin Wåhlén

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P2860

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

Variation in FTO contributes to childhood obesity and severe adult obesity

Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

Gender differences in fat metabolism.

Human adipose triglyceride lipase (PNPLA2) is not regulated by obesity and exhibits low in vitro triglyceride hydrolase activity.

A role of lipin in human obesity and insulin resistance: relation to adipocyte glucose transport and GLUT4 expression.

Do regional differences in adipocyte biology provide new pathophysiological insights?

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607-611

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scholarly article

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10.1194/JLR.M700448-JLR200

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3

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49

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2007-11-29T00:00:00Z

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