Physiologically-Based Pharmacokinetic (PBPK) Modeling and Simulations Principles, Methods, and Applications in the Pharmaceutical Industry.
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Network-based approaches in drug discovery and early developmentData-Driven Method to Estimate Nonlinear Chemical EquivalenceThe spacing principle for unlearning abnormal neuronal synchrony.Database of Optimized Proteomic Quantitative Methods for Human Drug Disposition-Related Proteins for Applications in Physiologically Based Pharmacokinetic Modeling.A survey of renal impairment pharmacokinetic studies for new oncology drug approvals in the USA from 2010 to early 2015: a focus on development strategies and future directionsImportance of Drug Pharmacokinetics at the Site of ActionApplications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug concentrations on drug responses and variabilityDistributions of Autocorrelated First-Order Kinetic Outcomes: Illness Severity.A physiologically based pharmacokinetic model for capreomycin.Physiological fidelity or model parsimony? The relative performance of reverse-toxicokinetic modeling approaches.A physiome interoperability roadmap for personalized drug development.Semi-mechanistic kidney model incorporating physiologically-relevant fluid reabsorption and transporter-mediated renal reabsorption: pharmacokinetics of γ-hydroxybutyric acid and L-lactate in ratsA whole-body physiologically based pharmacokinetic (WB-PBPK) model of ciprofloxacin: a step towards predicting bacterial killing at sites of infection.Prediction of pharmacokinetics and drug-drug interactions when hepatic transporters are involved.A novel approach for estimating ingested dose associated with paracetamol overdose.Does the Systemic Plasma Profile Inform the Liver Profile? Analysis Using a Physiologically Based Pharmacokinetic Model and Individual Compounds.CPT: Pharmacometrics & Systems Pharmacology Publishes Its 100th Article.Multiorgan Microphysiological Systems for Drug Development: Strategies, Advances, and Challenges.On the analysis of complex biological supply chains: From Process Systems Engineering to Quantitative Systems Pharmacology.Effects of renal impairment on transporter-mediated renal reabsorption of drugs and renal drug-drug interactions: A simulation-based study.Statistical relationship between metabolic decomposition and chemical uptake predicts bioconcentration factor data for diverse chemical exposures
P2860
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P2860
Physiologically-Based Pharmacokinetic (PBPK) Modeling and Simulations Principles, Methods, and Applications in the Pharmaceutical Industry.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Physiologically-Based Pharmaco ...... n the Pharmaceutical Industry.
@en
Physiologically-Based Pharmaco ...... n the Pharmaceutical Industry.
@nl
type
label
Physiologically-Based Pharmaco ...... n the Pharmaceutical Industry.
@en
Physiologically-Based Pharmaco ...... n the Pharmaceutical Industry.
@nl
prefLabel
Physiologically-Based Pharmaco ...... n the Pharmaceutical Industry.
@en
Physiologically-Based Pharmaco ...... n the Pharmaceutical Industry.
@nl
P356
P1476
Physiologically-Based Pharmaco ...... n the Pharmaceutical Industry.
@en
P2093
P356
10.1038/PSP.2013.29
P577
2013-07-10T00:00:00Z