Thymidylate synthase catalyzed H-transfers: two chapters in one tale.
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A Remote Mutation Affects the Hydride Transfer by Disrupting Concerted Protein Motions in Thymidylate SynthaseMg 2+ Binds to the Surface of Thymidylate Synthase and Affects Hydride Transfer at the Interior Active SiteEffects of the donor-acceptor distance and dynamics on hydride tunneling in the dihydrofolate reductase catalyzed reactionQM/MM calculations suggest a novel intermediate following the proton abstraction catalyzed by thymidylate synthaseStructural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii.Mechanism of the Swern oxidation: significant deviations from transition state theory.Role of dynamics in enzyme catalysis: substantial versus semantic controversies.Isotope effects as probes for enzyme catalyzed hydrogen-transfer reactions.Kinetic isotope effects as a probe of hydrogen transfers to and from common enzymatic cofactorsMechanisms and inhibition of uracil methylating enzymes.Relationship of femtosecond-picosecond dynamics to enzyme-catalyzed H-transfer.Computational replication of the abnormal secondary kinetic isotope effects in a hydride transfer reaction in solution with a motion assisted H-tunneling model.Role of long-range protein dynamics in different thymidylate synthase catalyzed reactions.A fast chemoenzymatic synthesis of [11C]-N5,N10-methylenetetrahydrofolate as a potential PET tracer for proliferating cells.Activation of Two Sequential H-transfers in the Thymidylate Synthase Catalyzed Reaction.Hydrogen donor-acceptor fluctuations from kinetic isotope effects: a phenomenological model.Examinations of the Chemical Step in Enzyme Catalysis.The general base in the thymidylate synthase catalyzed proton abstraction.A classical but new kinetic equation for hydride transfer reactions.Effect of pH on hydride transfer by Escherichia coli dihydrofolate reductase.Bacterial versus human thymidylate synthase: Kinetics and functionality.
P2860
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P2860
Thymidylate synthase catalyzed H-transfers: two chapters in one tale.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Thymidylate synthase catalyzed H-transfers: two chapters in one tale.
@en
Thymidylate synthase catalyzed H-transfers: two chapters in one tale.
@nl
type
label
Thymidylate synthase catalyzed H-transfers: two chapters in one tale.
@en
Thymidylate synthase catalyzed H-transfers: two chapters in one tale.
@nl
prefLabel
Thymidylate synthase catalyzed H-transfers: two chapters in one tale.
@en
Thymidylate synthase catalyzed H-transfers: two chapters in one tale.
@nl
P2860
P356
P1476
Thymidylate synthase catalyzed H-transfers: two chapters in one tale.
@en
P2093
Amnon Kohen
P2860
P304
P356
10.1021/JA103010B
P407
P577
2010-07-01T00:00:00Z