Effect of pH on hydride transfer by Escherichia coli dihydrofolate reductase.
about
Toward resolving the catalytic mechanism of dihydrofolate reductase using neutron and ultrahigh-resolution X-ray crystallography.Evidence that a 'dynamic knockout' in Escherichia coli dihydrofolate reductase does not affect the chemical step of catalysis.Escherichia coli dihydrofolate reductase catalyzed proton and hydride transfers: temporal order and the roles of Asp27 and Tyr100.The role of large-scale motions in catalysis by dihydrofolate reductase.Unraveling the role of protein dynamics in dihydrofolate reductase catalysisHydride Transfer in DHFR by Transition Path Sampling, Kinetic Isotope Effects, and Heavy Enzyme StudiesProtein dynamics and enzymatic chemical barrier passage.Different dynamical effects in mesophilic and hyperthermophilic dihydrofolate reductases.Thermal adaptation of dihydrofolate reductase from the moderate thermophile Geobacillus stearothermophilus.Increased dynamic effects in a catalytically compromised variant of Escherichia coli dihydrofolate reductase.The role of the Met20 loop in the hydride transfer in Escherichia coli dihydrofolate reductase.Protein motions and dynamic effects in enzyme catalysis.Reduced susceptibility of Moritella profunda dihydrofolate reductase to trimethoprim is not due to glutamate 28.
P2860
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P2860
Effect of pH on hydride transfer by Escherichia coli dihydrofolate reductase.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
Effect of pH on hydride transfer by Escherichia coli dihydrofolate reductase.
@en
Effect of pH on hydride transfer by Escherichia coli dihydrofolate reductase.
@nl
type
label
Effect of pH on hydride transfer by Escherichia coli dihydrofolate reductase.
@en
Effect of pH on hydride transfer by Escherichia coli dihydrofolate reductase.
@nl
prefLabel
Effect of pH on hydride transfer by Escherichia coli dihydrofolate reductase.
@en
Effect of pH on hydride transfer by Escherichia coli dihydrofolate reductase.
@nl
P2860
P356
P1433
P1476
Effect of pH on hydride transfer by Escherichia coli dihydrofolate reductase
@en
P2093
Rudolf K Allemann
P2860
P304
P356
10.1002/CBIC.201000794
P577
2011-04-19T00:00:00Z