Evidence for a tyrosine-adenine stacking interaction and for a short-lived open intermediate subsequent to initial binding of Escherichia coli RNA polymerase to promoter DNA
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Multiple base-recognition sites in a biological nanopore: two heads are better than oneInitial events in bacterial transcription initiationStructural Basis for Promoter −10 Element Recognition by the Bacterial RNA Polymerase σ SubunitOne-step DNA melting in the RNA polymerase cleft opens the initiation bubble to form an unstable open complex.Promoter melting triggered by bacterial RNA polymerase occurs in three steps.Multiple roles of the RNA polymerase {beta}' SW2 region in transcription initiation, promoter escape, and RNA elongation.Interaction of Escherichia coli RNA polymerase σ70 subunit with promoter elements in the context of free σ70, RNA polymerase holoenzyme, and the β'-σ70 complex.Next generation sequencing-based parallel analysis of melting kinetics of 4096 variants of a bacterial promoter.Differential role of base pairs on gal promoters strengthBase flipping in open complex formation at bacterial promotersPredicting the strength of UP-elements and full-length E. coli σE promoters.RNA polymerase molecular beacon as tool for studies of RNA polymerase-promoter interactions.Structure of a bacterial RNA polymerase holoenzyme open promoter complex.Mechanism of bacterial transcription initiation: RNA polymerase - promoter binding, isomerization to initiation-competent open complexes, and initiation of RNA synthesisReduced capacity of alternative sigmas to melt promoters ensures stringent promoter recognition.Archaeal RNA polymerase.Fluorescent DNA-based enzyme sensors.Inter-sigmulon communication through topological promoter coupling.Indirect read-out of the promoter DNA by RNA polymerase in the closed complex.Probing DNA binding, DNA opening, and assembly of a downstream clamp/jaw in Escherichia coli RNA polymerase-lambdaP(R) promoter complexes using salt and the physiological anion glutamate.The transcription inhibitor lipiarmycin blocks DNA fitting into the RNA polymerase catalytic siteDistinct functions of regions 1.1 and 1.2 of RNA polymerase σ subunits from Escherichia coli and Thermus aquaticus in transcription initiation.DNA melting by RNA polymerase at the T7A1 promoter precedes the rate-limiting step at 37 degrees C and results in the accumulation of an off-pathway intermediate.Promoter recognition by bacterial alternative sigma factors: the price of high selectivity?Antibiotics trapping transcription initiation intermediates: To melt or to bend, what's first?A hyper-mutant of the unusual sigma70-Pr promoter bypasses synergistic ppGpp/DksA co-stimulation.Conformational heterogeneity and bubble dynamics in single bacterial transcription initiation complexes.Base Flipping
P2860
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P2860
Evidence for a tyrosine-adenine stacking interaction and for a short-lived open intermediate subsequent to initial binding of Escherichia coli RNA polymerase to promoter DNA
description
2008 nî lūn-bûn
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2008年の論文
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2008年論文
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2008年論文
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2008年論文
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2008年論文
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2008年論文
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2008年论文
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2008年论文
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2008年论文
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name
Evidence for a tyrosine-adenin ...... RNA polymerase to promoter DNA
@en
Evidence for a tyrosine-adenin ...... RNA polymerase to promoter DNA
@nl
type
label
Evidence for a tyrosine-adenin ...... RNA polymerase to promoter DNA
@en
Evidence for a tyrosine-adenin ...... RNA polymerase to promoter DNA
@nl
prefLabel
Evidence for a tyrosine-adenin ...... RNA polymerase to promoter DNA
@en
Evidence for a tyrosine-adenin ...... RNA polymerase to promoter DNA
@nl
P2093
P2860
P1476
Evidence for a tyrosine-adenin ...... RNA polymerase to promoter DNA
@en
P2093
Lisa A Schroeder
M Thomas Record
Michael E Harris
Pieter L DeHaseth
Ruth M Saecker
Theodore J Gries
P2860
P304
P356
10.1016/J.JMB.2008.10.023
P407
P577
2008-10-17T00:00:00Z