Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia.
about
Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell responseThe CD47-SIRPα pathway in cancer immune evasion and potential therapeutic implicationsTherapeutic opportunities for targeting the ubiquitous cell surface receptor CD47Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcomaExtranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapyThrombospondin-1 signaling through CD47 inhibits self-renewal by regulating c-Myc and other stem cell transcription factorsStem cell technology in breast cancer: current status and potential applicationsTherapies targeting cancer stem cells: Current trends and future challengesImmunotargeting of cancer stem cellsTargeting the innate immune system as immunotherapy for acute myeloid leukemiaBoth the apoptotic suicide pathway and phagocytosis are required for a programmed cell death in Caenorhabditis elegans.CD47 update: a multifaceted actor in the tumour microenvironment of potential therapeutic interestCD47 expression in cryopreserved equine cutaneous masses and normal skinThe CD47-binding peptide of thrombospondin-1 induces defenestration of liver sinusoidal endothelial cellsRegistered report: the CD47-signal regulated protein alpha (SIRPa) interaction is a therapeutic target for human solid tumorsClearing the dead: apoptotic cell sensing, recognition, engulfment, and digestionCD244 maintains the proliferation ability of leukemia initiating cells through SHP-2/p27kip1 signaling.Anti-CD47 Antibody As a Targeted Therapeutic Agent for Human Lung Cancer and Cancer Stem Cells.Immune checkpoint blockade for hematologic malignancies: a reviewApoptotic death of cancer stem cells for cancer therapy.Identification of CD166 as a surface marker for enriching prostate stem/progenitor and cancer initiating cellsCo-expression of MET and CD47 is a novel prognosticator for survival of luminal breast cancer patientsEngagement of SIRPα inhibits growth and induces programmed cell death in acute myeloid leukemia cells.Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors.CD47 in the tumor microenvironment limits cooperation between antitumor T-cell immunity and radiotherapyIdentification of CD34+ and CD34- leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemiaEnhancing effect of β-elemene emulsion on chemotherapy with harringtonine, aclacinomycin, and Ara-c in treatment of refractory/relapsed acute myeloid leukemia.Macrophages eat cancer cells using their own calreticulin as a guide: roles of TLR and Btk.Noninvasive bioluminescent imaging of primary patient acute lymphoblastic leukemia: a strategy for preclinical modeling.Human cancer growth and therapy in immunodeficient mouse models.CD47-signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction.Breast cancer stem cells, cytokine networks, and the tumor microenvironment."Velcro" engineering of high affinity CD47 ectodomain as signal regulatory protein α (SIRPα) antagonists that enhance antibody-dependent cellular phagocytosisNanoparticle-induced intraperitoneal hyperthermia and targeted photoablation in treating ovarian cancer.Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential.Cluster of differentiation 96 as a leukemia stem cell-specific marker and a factor for prognosis evaluation in leukemia.RBP2 Promotes Adult Acute Lymphoblastic Leukemia by Upregulating BCL2.Immunotherapy targets in pediatric cancer.CD47 is an adverse prognostic factor and a therapeutic target in gastric cancer.CD47 blockade triggers T cell-mediated destruction of immunogenic tumors.
P2860
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P2860
Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia.
@en
Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia.
@nl
type
label
Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia.
@en
Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia.
@nl
prefLabel
Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia.
@en
Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia.
@nl
P2093
P2860
P1433
P1476
Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia.
@en
P2093
Ash A Alizadeh
Christopher Y Park
Feifei Zhao
Irving L Weissman
Mark P Chao
Rachel Weissman-Tsukamoto
Ravindra Majeti
P2860
P304
P356
10.1158/0008-5472.CAN-10-2238
P407
P577
2010-12-21T00:00:00Z