Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
about
RB1: a prototype tumor suppressor and an enigmamTORC1 and mTORC2 in cancer and the tumor microenvironment.The Strange Case of CDK4/6 Inhibitors: Mechanisms, Resistance, and Combination Strategies.The intersection of RB tumor suppressor function, stem cells, metabolism and inflammation.Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells.Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and Survival.MiR-101 reduces cell proliferation and invasion and enhances apoptosis in endometrial cancer via regulating PI3K/Akt/mTOR.Use of dual mTOR inhibitor MLN0128 against everolimus-resistant breast cancer.Role of mTOR Complexes in Neurogenesis.The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells.FGF9/FGFR2 increase cell proliferation by activating ERK1/2, Rb/E2F1, and cell cycle pathways in mouse Leydig tumor cells
P2860
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P2860
Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
@en
Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
@nl
type
label
Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
@en
Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
@nl
prefLabel
Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
@en
Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
@nl
P2093
P2860
P1433
P1476
Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt
@en
P2093
Alex Toker
Christian Berrios
James A DeCaprio
Jianping Guo
Jinfang Zhang
Pengda Liu
Piotr Sicinski
P2860
P304
P356
10.1016/J.MOLCEL.2016.04.023
P577
2016-05-26T00:00:00Z