Molecular cloning, expression, and characterization of the authentic hyaluronan synthase from group C Streptococcus equisimilis.
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Genetic basis for hyper production of hyaluronic acid in natural and engineered microorganismsHyaluronan Synthase: The Mechanism of Initiation at the Reducing End and a Pendulum Model for Polysaccharide Translocation to the Cell ExteriorInsights into the structure and function of membrane-integrated processive glycosyltransferases.Masquerading microbial pathogens: capsular polysaccharides mimic host-tissue moleculesFUN26 (function unknown now 26) protein from saccharomyces cerevisiae is a broad selectivity, high affinity, nucleoside and nucleobase transporter.The streptococcal hyaluronan synthases are inhibited by sulfhydryl-modifying reagents, but conserved cysteine residues are not essential for enzyme function.Site-directed mutation of conserved cysteine residues does not inactivate the Streptococcus pyogenes hyaluronan synthase.Topological organization of the hyaluronan synthase from Streptococcus pyogenes.Purification and lipid dependence of the recombinant hyaluronan synthases from Streptococcus pyogenes and Streptococcus equisimilis.The active streptococcal hyaluronan synthases (HASs) contain a single HAS monomer and multiple cardiolipin molecules.Mutation of two intramembrane polar residues conserved within the hyaluronan synthase family alters hyaluronan product size.A high-throughput screen for hyaluronic acid accumulation in recombinant Escherichia coli transformed by libraries of engineered sigma factors.Complete genome sequencing and analysis of a Lancefield group G Streptococcus dysgalactiae subsp. equisimilis strain causing streptococcal toxic shock syndrome (STSS).Hyaluronic acid production in Bacillus subtilisIdentification of a membrane-localized cysteine cluster near the substrate-binding sites of the Streptococcus equisimilis hyaluronan synthaseClustered Conserved Cysteines in Hyaluronan Synthase Mediate Cooperative Activation by Mg(2+) Ions and Severe Inhibitory Effects of Divalent CationsHyaluronan synthase polymerizing activity and control of product size are discrete enzyme functions that can be uncoupled by mutagenesis of conserved cysteinesEvolution of glycosaminoglycans and their glycosyltransferases: Implications for the extracellular matrices of animals and the capsules of pathogenic bacteria.Characterization of the purified hyaluronan synthase from Streptococcus equisimilis.Hyaluronan biosynthesis by class I streptococcal hyaluronan synthases occurs at the reducing end.Glycosaminoglycan polysaccharide biosynthesis and production: today and tomorrow.Insight into hyaluronic acid molecular weight control.O-antigen polymerase adopts a distributive mechanism for lipopolysaccharide biosynthesis.Development of a CRISPR-Cas9 Tool Kit for Comprehensive Engineering of Bacillus subtilis.Tts, a processive beta-glucosyltransferase of Streptococcus pneumoniae, directs the synthesis of the branched type 37 capsular polysaccharide in Pneumococcus and other gram-positive species.Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone.The role of hyaluronic acid precursor concentrations in molecular weight control in Streptococcus zooepidemicus.Engineering of cell membrane to enhance heterologous production of hyaluronic acid in Bacillus subtilis.Phospholipid dependence and liposome reconstitution of purified hyaluronan synthase.Production Methods for Hyaluronan
P2860
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P2860
Molecular cloning, expression, and characterization of the authentic hyaluronan synthase from group C Streptococcus equisimilis.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Molecular cloning, expression, ...... p C Streptococcus equisimilis.
@en
Molecular cloning, expression, ...... p C Streptococcus equisimilis.
@nl
type
label
Molecular cloning, expression, ...... p C Streptococcus equisimilis.
@en
Molecular cloning, expression, ...... p C Streptococcus equisimilis.
@nl
prefLabel
Molecular cloning, expression, ...... p C Streptococcus equisimilis.
@en
Molecular cloning, expression, ...... p C Streptococcus equisimilis.
@nl
P2860
P356
P1476
Molecular cloning, expression, ...... p C Streptococcus equisimilis.
@en
P2093
P2860
P304
32539-32546
P356
10.1074/JBC.272.51.32539
P407
P577
1997-12-01T00:00:00Z